Antibody escape and cryptic cross-domain stabilization in the SARS-CoV-2 Omicron spike protein
- Kamyab Javanmardi, Thomas H Segall-Shapiro, Chia-Wei Chou, …, Andrew D Ellington, Ilya J Finkelstein, Jimmy D Gollihar
- Cell Host Microbe, 10.1016/j.chom.2022.07.016
Author Correction: Engineered promoters enable constant gene expression at any copy number in bacteria
- Thomas H Segall-Shapiro, Eduardo D Sontag, Christopher A Voigt
- Nat Biotechnol, 10.1038/s41587-022-01300-7
Selection for constrained peptides that bind to a single target protein
- Andrew M King, Daniel A Anderson, Emerson Glassey, …, Thomas L Williams, D Benjamin Gordon, Christopher A Voigt
- Nat Commun, 10.1038/s41467-021-26350-4
Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality
- Jule Goike, Ching-Lin Hsieh, Andrew Horton, …, Daniel R Boutz, Jason S McLellan, Jimmy D Gollihar
- None, 10.1101/2021.04.07.438849
The Structure of a Thermophilic Kinase Shapes Fitness upon Random Circular Permutation
- Alicia M Jones, Manan M Mehta, Emily E Thomas, …, Thomas H Segall-Shapiro, Shirley Liu, Jonathan J Silberg
- ACS Synth Biol, 10.1021/acssynbio.5b00305
TREC-IN: gene knock-in genetic tool for genomes cloned in yeast
- Suchismita Chandran, Vladimir N Noskov, Thomas H Segall-Shapiro, …, Joerg Jores, Sanjay Vashee, Ray-Yuan Chuang
- BMC Genomics, 10.1186/1471-2164-15-1180
Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression
- Alec A K Nielsen, Thomas H Segall-Shapiro, Christopher A Voigt
- Curr Opin Chem Biol, 10.1016/j.cbpa.2013.10.003
A genetically encoded and gate for cell-targeted metabolic labeling of proteins
- Alborz Mahdavi, Thomas H Segall-Shapiro, Songzi Kou, …, Rustem F Ismagilov, Jonathan J Silberg, David A Tirrell
- J Am Chem Soc, 10.1021/ja400448f
An adaptor from translational to transcriptional control enables predictable assembly of complex regulation
- Chang C Liu, Lei Qi, Julius B Lucks, …, Denise Wang, Vivek K Mutalik, Adam P Arkin
- Nat Methods, 10.1038/nmeth.2184
Modular control of multiple pathways using engineered orthogonal T7 polymerases
- Karsten Temme, Rena Hill, Thomas H Segall-Shapiro, Felix Moser, Christopher A Voigt
- Nucleic Acids Res, 10.1093/nar/gks597
Mesophilic and hyperthermophilic adenylate kinases differ in their tolerance to random fragmentation
- Thomas H Segall-Shapiro, Peter Q Nguyen, Edgardo D Dos Santos, …, Justin Judd, Junghae Suh, Jonathan J Silberg
- J Mol Biol, 10.1016/j.jmb.2010.11.057
Creation of a bacterial cell controlled by a chemically synthesized genome
- Daniel G Gibson, John I Glass, Carole Lartigue, …, Clyde A Hutchison, Hamilton O Smith, J Craig Venter
- Science, 10.1126/science.1190719
Tandem repeat coupled with endonuclease cleavage (TREC): a seamless modification tool for genome engineering in yeast
- Vladimir N Noskov, Thomas H Segall-Shapiro, Ray-Yuan Chuang
- Nucleic Acids Res, 10.1093/nar/gkq099