An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis
- Shuang Wang, Kenneth Li, Eliana Pickholz, …, Miri Adler, Ruslan Medzhitov, Scott L Friedman
- Sci Transl Med, 10.1126/scitranslmed.add3949
Manipulating and tracking single hepatocyte behavior during mouse liver regeneration by performing hydrodynamic tail vein injection
- Shuang Wang, Marina Ruiz de Galarreta, Kirsten C Sadler, Amaia Lujambio
- STAR Protoc, 10.1016/j.xpro.2021.100440
Hepatic fibrosis: A convergent response to liver injury that is reversible
- Shuang Wang, Scott L Friedman
- J Hepatol, 10.1016/j.jhep.2020.03.011
Taming the Savage Breast From Within: Transcription Factor 21, a Regulator of Stellate Cell Deactivation
- Shuang Wang, Scott L Friedman
- Hepatology, 10.1002/hep.31151
Epigenetic Compensation Promotes Liver Regeneration
- Shuang Wang, Chi Zhang, Dan Hasson, …, Amaia Lujambio, Emily Bernstein, Kirsten C Sadler
- Dev Cell, 10.1016/j.devcel.2019.05.034
Primary aromatic amines and cancer: Novel mechanistic insights using 4-aminobiphenyl as a model carcinogen
- Shuang Wang, Daniel Hanna, Kim S Sugamori, Denis M Grant
- Pharmacol Ther, 10.1016/j.pharmthera.2019.05.004
Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling
- Yelena Chernyavskaya, Raksha Mudbhary, Chi Zhang, …, Jeffrey A Yoder, Yujin Hoshida, Kirsten C Sadler
- Development, 10.1242/dev.147629
Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
- Shuang Wang, Debbie Bott, Aveline Tung, Kim S Sugamori, Denis M Grant
- Drug Metab Dispos, 10.1124/dmd.115.063297
N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer
- Shuang Wang, Kim S Sugamori, Aveline Tung, J Peter McPherson, Denis M Grant
- Toxicol Sci, 10.1093/toxsci/kfv006
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
- Shinichiro Ogawa, James Surapisitchat, Carl Virtanen, …, Rachel F Tyndale, Denis M Grant, Gordon Keller
- Development, 10.1242/dev.090266