APOBEC mutagenesis is a common process in normal human small intestine
- Iñigo Martincorena
- Peter J Campbell
- January 26, 2023
- kedalionlabs.com
- Yichen Wang, Philip S Robinson, Tim H H Coorens, …, Matthias Zilbauer, Simon James Alexander Buczacki, Michael R Stratton
- Nat Genet, 10.1038/s41588-022-01296-5
Mapping single-cell transcriptomes in the intra-tumoral and associated territories of kidney cancer
- Peter J Campbell
- November 24, 2022
- kedalionlabs.com
- Ruoyan Li, John R Ferdinand, Kevin W Loudon, …, Peter J Campbell, Sarah A Teichmann, Thomas J Mitchell
- Cancer Cell, 10.1016/j.ccell.2022.11.001
Spatial genomics maps the structure, nature and evolution of cancer clones
- Peter J Campbell
- Sandro Santagata
- Vitalii Kleshchevnikov
- November 9, 2022
- kedalionlabs.com
- Artem Lomakin, Jessica Svedlund, Carina Strell, …, Moritz Gerstung, Mats Nilsson, Lucy R Yates
- Nature, 10.1038/s41586-022-05425-2
Clonal diversification and histogenesis of malignant germ cell tumours
- Alex Cagan
- Peter J Campbell
- August 11, 2022
- kedalionlabs.com
- Thomas R W Oliver, Lia Chappell, Rashesh Sanghvi, …, Peter J Campbell, Raheleh Rahbari, Sam Behjati
- Nat Commun, 10.1038/s41467-022-31375-4
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia
- Peter J Campbell
- August 11, 2022
- kedalionlabs.com
- Ferran Nadeu, Romina Royo, Ramon Massoni-Badosa, …, Francesco Maura, José I Martín-Subero, Elías Campo
- Nat Med, 10.1038/s41591-022-01927-8
Diverse mutational landscapes in human lymphocytes
- Alex Cagan
- Iñigo Martincorena
- Peter J Campbell
- August 10, 2022
- kedalionlabs.com
- Heather E Machado, Emily Mitchell, Nina F Øbro, …, Daniel J Hodson, David G Kent, Peter J Campbell
- Nature, 10.1038/s41586-022-05072-7
Unified classification and risk-stratification in Acute Myeloid Leukemia
- Peter J Campbell
- August 8, 2022
- kedalionlabs.com
- Yanis Tazi, Juan E Arango-Ossa, Yangyu Zhou, …, Sean M Devlin, Brian J P Huntly, Elli Papaemmanuil
- Nat Commun, 10.1038/s41467-022-32103-8
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells
- Peter J Campbell
- July 8, 2022
- kedalionlabs.com
- Philip S Robinson, Laura E Thomas, Federico Abascal, …, Iñigo Martincorena, Julian R Sampson, Michael R Stratton
- Nat Commun, 10.1038/s41467-022-31341-0
Clonal dynamics of haematopoiesis across the human lifespan
- Alex Cagan
- Peter J Campbell
- June 1, 2022
- kedalionlabs.com
- Emily Mitchell, Michael Spencer Chapman, Nicholas Williams, …, Jyoti Nangalia, Elisa Laurenti, Peter J Campbell
- Nature, 10.1038/s41586-022-04786-y
The longitudinal dynamics and natural history of clonal haematopoiesis
- Peter J Campbell
- June 1, 2022
- kedalionlabs.com
- Margarete A Fabre, José Guilherme de Almeida, Edoardo Fiorillo, …, Francesco Cucca, Moritz Gerstung, George S Vassiliou
- Nature, 10.1038/s41586-022-04785-z
Mutational landscape of normal epithelial cells in Lynch Syndrome patients
- Peter J Campbell
- May 17, 2022
- kedalionlabs.com
- Bernard C H Lee, Philip S Robinson, Tim H H Coorens, …, Siu Tsan Yuen, Suet Yi Leung, Michael R Stratton
- Nat Commun, 10.1038/s41467-022-29920-2
Bayesian networks elucidate complex genomic landscapes in cancer
- Peter J Campbell
- April 5, 2022
- kedalionlabs.com
- Nicos Angelopoulos, Aikaterini Chatzipli, Jyoti Nangalia, Francesco Maura, Peter J Campbell
- Commun Biol, 10.1038/s42003-022-03243-w
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
- Peter J Campbell
- November 26, 2021
- kedalionlabs.com
- Eva G Álvarez, Jonas Demeulemeester, Paula Otero, …, Hidewaki Nakagawa, Peter Van Loo, Jose M C Tubio
- Nat Commun, 10.1038/s41467-021-26805-8
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases
- Peter J Campbell
- October 1, 2021
- kedalionlabs.com
- Philip S Robinson, Tim H H Coorens, Claire Palles, …, Iñigo Martincorena, Ian Tomlinson, Michael R Stratton
- Nat Genet, 10.1038/s41588-021-00930-y