Scholar: Noam Prywes

Noam Prywes

Academic lineage

Rubisco Function, Evolution, and Engineering

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Rapid detection of SARS-CoV-2 RNA in saliva via Cas13

  • Sita S Chandrasekaran, Shreeya Agrawal, Alison Fanton, …, Jennifer A Doudna, David F Savage, Patrick D Hsu
  • Nat Biomed Eng, 10.1038/s41551-022-00917-y
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Accelerated RNA detection using tandem CRISPR nucleases

  • Tina Y Liu, Gavin J Knott, Dylan C J Smock, …, Patrick D Hsu, David F Savage, Jennifer A Doudna
  • Nat Chem Biol, 10.1038/s41589-021-00842-2
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Highly active rubiscos discovered by systematic interrogation of natural sequence diversity

  • Dan Davidi, Melina Shamshoum, Zhijun Guo, …, Itai Sharon, Oliver Mueller-Cajar, Ron Milo
  • EMBO J, 10.15252/embj.2019104081
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Revisiting Trade-offs between Rubisco Kinetic Parameters

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Transfer of Sequence Information and Replication of Diimine Duplexes

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Copying of Mixed-Sequence RNA Templates inside Model Protocells

  • Derek K O’Flaherty, Neha P Kamat, Fatima N Mirza, Li Li, Noam Prywes, Jack W Szostak
  • J Am Chem Soc, 10.1021/jacs.8b00639
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The genetic basis for the adaptation of E. coli to sugar synthesis from CO 2

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Enhanced Nonenzymatic RNA Copying with 2-Aminoimidazole Activated Nucleotides

  • Li Li, Noam Prywes, Chun Pong Tam, …, Enver Cagri Izgu, Ayan Pal, Jack W Szostak
  • J Am Chem Soc, 10.1021/jacs.6b13148
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Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides

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Thiolated uridine substrates and templates improve the rate and fidelity of ribozyme-catalyzed RNA copying

  • Noam Prywes, Yale S Michaels, Ayan Pal, Seung Soo Oh, Jack W Szostak
  • Chem Commun (Camb), 10.1039/c6cc02692c
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Experimental and Computational Evidence for a Loose Transition State in Phosphoroimidazolide Hydrolysis

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Chain-length heterogeneity allows for the assembly of fatty acid vesicles in dilute solutions

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Translation factors direct intrinsic ribosome dynamics during translation termination and ribosome recycling

  • Samuel H Sternberg, Jingyi Fei, Noam Prywes, Kelly A McGrath, Ruben L Gonzalez
  • Nat Struct Mol Biol, 10.1038/nsmb.1622
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