DNA damage and repair in age-related inflammation
- Yang Zhao, Matthew Simon, Yang Zhao, …, Matthew Simon, Andrei Seluanov, Vera Gorbunova
- Nat Rev Immunol, 10.1038/s41577-022-00751-y
Accurate Proteomewide Measurement of Methionine Oxidation in Aging Mouse Brains
- John Q Bettinger, Matthew Simon, Anatoly Korotkov, …, Andrei Seluanov, Vera Gorbunova, Sina Ghaemmaghami
- J Proteome Res, 10.1021/acs.jproteome.2c00127
Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation
- J Yuyang Lu, Matthew Simon, Yang Zhao, …, Richard A Miller, Andrei Seluanov, Vera Gorbunova
- Cell Metab, 10.1016/j.cmet.2022.04.011
Author Correction: L1 drives IFN in senescent cells and promotes age-associated inflammation
- Marco De Cecco, Takahiro Ito, Anna P Petrashen, …, Stephen L Helfand, Nicola Neretti, John M Sedivy
- Nature, 10.1038/s41586-019-1350-9
SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170
- Sarallah Rezazadeh, David Yang, Gregory Tombline, …, Sean P Regan, Andrei Seluanov, Vera Gorbunova
- Nucleic Acids Res, 10.1093/nar/gkz528
SIRT6 Is Responsible for More Efficient DNA Double-Strand Break Repair in Long-Lived Species
- Xiao Tian, Denis Firsanov, Zhihui Zhang, …, Vadim N Gladyshev, Andrei Seluanov, Vera Gorbunova
- Cell, 10.1016/j.cell.2019.03.043
The meiotic phosphatase GSP-2/PP1 promotes germline immortality and small RNA-mediated genome silencing
- Katherine Kretovich Billmyre, Anna-Lisa Doebley, Maya Spichal, …, Peter Mark Carlton, Peter Sarkies, Shawn Ahmed
- PLoS Genet, 10.1371/journal.pgen.1008004
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
- Matthew Simon, Michael Van Meter, Julia Ablaeva, …, John M Sedivy, Andrei Seluanov, Vera Gorbunova
- Cell Metab, 10.1016/j.cmet.2019.02.014
Transgenerational Sterility of Piwi Mutants Represents a Dynamic Form of Adult Reproductive Diapause
- Bree Heestand, Matt Simon, Stephen Frenk, Denis Titov, Shawn Ahmed
- Cell Rep, 10.1016/j.celrep.2018.03.015
JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks
- Michael Van Meter, Matthew Simon, Gregory Tombline, …, Vilhelm A Bohr, Vera Gorbunova, Andrei Seluanov
- Cell Rep, 10.1016/j.celrep.2016.08.006
Reduced insulin/IGF-1 signaling restores germ cell immortality to Caenorhabditis elegans Piwi mutants
- Matt Simon, Peter Sarkies, Kohta Ikegami, …, Aisa Sakaguchi, Eric A Miska, Shawn Ahmed
- Cell Rep, 10.1016/j.celrep.2014.03.056