Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy
- Karthickeyan Chella Krishnan, Elie-Julien El Hachem, Mark Keller, …, Benjamin Parker, David E James, Aldons J Lusis
- Elife, 10.7554/elife.82619
Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice
- Timothy M Moore, Sindre Lee, Thomas Olsen, …, Christian A Drevon, Aldons J Lusis, Andrea L Hevener
- Cell Rep, 10.1016/j.celrep.2023.112499
The potential of integrating human and mouse discovery platforms to advance our understanding of cardiometabolic diseases
- Aaron W Jurrjens, Marcus M Seldin, Corey Giles, …, Peter J Meikle, Brian G Drew, Anna C Calkin
- Elife, 10.7554/elife.86139
Author Correction: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut
- Qijun Zhang, Vanessa Linke, Katherine A Overmyer, …, Alan D Attie, Joshua J Coon, Federico E Rey
- Nat Microbiol, 10.1038/s41564-023-01366-2
RNF130 Regulates LDLR Availability and Plasma LDL Cholesterol Levels
- Bethan L Clifford, Kelsey E Jarrett, Joan Cheng, …, Angel Baldan, Thomas Q de Aguiar Vallim, Elizabeth J Tarling
- Circ Res, 10.1161/circresaha.122.321938
APOBEC3B drives PKR-mediated translation shutdown and protects stress granules in response to viral infection
- Lavanya Manjunath, Sunwoo Oh, Pedro Ortega, …, Reuben S Harris, Bert L Semler, Rémi Buisson
- Nat Commun, 10.1038/s41467-023-36445-9
Dysregulated systemic metabolism in a Down syndrome mouse model
- Dylan C Sarver, Cheng Xu, Leandro M Velez, …, Marcus M Seldin, Roger H Reeves, G William Wong
- Mol Metab, 10.1016/j.molmet.2022.101666
Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function
- Jeffrey Molendijk, Ronnie Blazev, Richard J Mills, …, David E James, Marcus M Seldin, Benjamin L Parker
- Elife, 10.7554/elife.82951
Liver-heart cross-talk mediated by coagulation factor XI protects against heart failure
- Yang Cao, Yuchen Wang, Zhenqi Zhou, …, Hooman Allayee, Marcus M Seldin, Aldons J Lusis
- Science, 10.1126/science.abn0910
Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer
- Sung Kook Chun, Bridget M Fortin, Rachel C Fellows, …, Marcus M Seldin, Marian L Waterman, Selma Masri
- Sci Adv, 10.1126/sciadv.abo2389
Tryptophan metabolism is a physiological integrator regulating circadian rhythms
- Paul Petrus, Marlene Cervantes, Muntaha Samad, …, Peter Kaiser, Cholsoon Jang, Paolo Sassone-Corsi
- Mol Metab, 10.1016/j.molmet.2022.101556
Sex differences in heart mitochondria regulate diastolic dysfunction
- Yang Cao, Laurent Vergnes, Yu-Chen Wang, …, Thomas M Vondriska, Karen Reue, Aldons J Lusis
- Nat Commun, 10.1038/s41467-022-31544-5
Genetic variation of putative myokine signaling is dominated by biological sex and sex hormones
- Leandro M Velez, Cassandra Van, Timothy Moore, …, Casey Johnson, Andrea L Hevener, Marcus M Seldin
- Elife, 10.7554/elife.76887