Academic lineage
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
- Albert M Li, Gregory S Ducker, Yang Li, …, Joshua D Rabinowitz, Craig B Thompson, Jiangbin Ye
- Mol Cancer Res, 10.1158/1541-7786.mcr-19-0606
Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity
- Qingkun Liu, Emily M Johnson, Rachel K Lam, …, Christoph Mueller, Michelle L James, Katrin I Andreasson
- Nat Immunol, 10.1038/s41590-019-0421-2
Macrophage de novo NAD + synthesis specifies immune function in aging and inflammation
- Paras S Minhas, Ling Liu, Peter K Moon, …, Daria Mochly-Rosen, Joshua D Rabinowitz, Katrin I Andreasson
- Nat Immunol, 10.1038/s41590-018-0255-3
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
- Antonio Davila, Ling Liu, Karthikeyani Chellappa, …, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
- Elife, 10.7554/elife.33246
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
- Ling Liu, Xiaoyang Su, William J Quinn, …, Timothy J Mitchison, Joseph A Baur, Joshua D Rabinowitz
- Cell Metab, 10.1016/j.cmet.2018.03.018
Chemical Basis for Deuterium Labeling of Fat and NADPH
- Zhaoyue Zhang, Li Chen, Ling Liu, Xiaoyang Su, Joshua D Rabinowitz
- J Am Chem Soc, 10.1021/jacs.7b08012
Enhancing CD8 + T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy
- Ying Zhang, Raj Kurupati, Ling Liu, …, Gordon J Freeman, Joshua D Rabinowitz, Hildegund C J Ertl
- Cancer Cell, 10.1016/j.ccell.2017.08.004
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle
- David W Frederick, Emanuele Loro, Ling Liu, …, Joshua D Rabinowitz, Tejvir S Khurana, Joseph A Baur
- Cell Metab, 10.1016/j.cmet.2016.07.005
Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage
- Ling Liu, Supriya Shah, Jing Fan, Junyoung O Park, Kathryn E Wellen, Joshua D Rabinowitz
- Nat Chem Biol, 10.1038/nchembio.2047
Human phosphoglycerate dehydrogenase produces the oncometabolite D-2-hydroxyglutarate
- Jing Fan, Xin Teng, Ling Liu, …, Ryan E Looper, Matthew G Vander Heiden, Joshua D Rabinowitz
- ACS Chem Biol, 10.1021/cb500683c
Zinc finger antiviral protein inhibits murine gammaherpesvirus 68 M2 expression and regulates viral latency in cultured cells
- Yifang Xuan, Ling Liu, Sheng Shen, Hongyu Deng, Guangxia Gao
- J Virol, 10.1128/jvi.01514-12