Scholar: Li Chen

Li Chen

Academic lineage

Metabolite discovery through global annotation of untargeted metabolomics data

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NAD + flux is maintained in aged mice despite lower tissue concentrations

  • Melanie R McReynolds, Karthikeyani Chellappa, Eric Chiles, …, Xiaoyang Su, Joshua D Rabinowitz, Joseph A Baur
  • Cell Syst, 10.1016/j.cels.2021.09.001
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Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity

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A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

  • Jonathan M Ghergurovich, Juan C García-Cañaveras, Joshua Wang, …, Ulf H Beier, Hahn Kim, Joshua D Rabinowitz
  • Nat Chem Biol, 10.1038/s41589-020-0533-x
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A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism

  • Andrew F Schober, Andrew D Mathis, Christine Ingle, …, Ivan Junier, Olivier Rivoire, Kimberly A Reynolds
  • Cell Rep, 10.1016/j.celrep.2019.05.030
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The Tumor Metabolic Microenvironment: Lessons from Lactate

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The metabolites NADP + and NADPH are the targets of the circadian protein Nocturnin (Curled)

  • Michael A Estrella, Jin Du, Li Chen, …, Paul Schedl, Joshua Rabinowitz, Alexei Korennykh
  • Nat Commun, 10.1038/s41467-019-10125-z
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NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism

  • Li Chen, Zhaoyue Zhang, Atsushi Hoshino, …, Michael Morley, Zoltan Arany, Joshua D Rabinowitz
  • Nat Metab,
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Chemical Basis for Deuterium Labeling of Fat and NADPH

  • Zhaoyue Zhang, Li Chen, Ling Liu, Xiaoyang Su, Joshua D Rabinowitz
  • J Am Chem Soc, 10.1021/jacs.7b08012
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An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate

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Photoaffinity labeling of transcription factors by DNA-templated crosslinking

  • Ying Liu, Wenlu Zheng, Wan Zhang, …, Xingshuo Chen, Haifeng Zheng, Xiaoyu Li
  • None, 10.1039/c4sc01953a
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Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors

  • Wenyun Lu, Lin Wang, Li Chen, Sheng Hui, Joshua D Rabinowitz
  • Antioxid Redox Signal, 10.1089/ars.2017.7014
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Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry

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