Academic lineage
Metabolite discovery through global annotation of untargeted metabolomics data
- Li Chen
- Lin Wang
- Wenyun Lu
- Xi Xing
- Xianfeng Zeng
- Xin Teng
- Yihui Shen
- October 29, 2021
- kedalionlabs.com
- Li Chen, Wenyun Lu, Lin Wang, …, Shawn R Campagna, Mona Singh, Joshua D Rabinowitz
- Nat Methods, 10.1038/s41592-021-01303-3
NAD + flux is maintained in aged mice despite lower tissue concentrations
- Connor Jankowski
- Karthikeyani Chellappa
- Li Chen
- Yihui Shen
- September 24, 2021
- kedalionlabs.com
- Melanie R McReynolds, Karthikeyani Chellappa, Eric Chiles, …, Xiaoyang Su, Joshua D Rabinowitz, Joseph A Baur
- Cell Syst, 10.1016/j.cels.2021.09.001
Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity
- Li Chen
- Lin Wang
- Wenyun Lu
- Xi Xing
- July 3, 2020
- kedalionlabs.com
- Wenyun Lu, Xi Xing, Lin Wang, …, Sisi Zhang, Melanie R McReynolds, Joshua D Rabinowitz
- Anal Chem, 10.1021/acs.analchem.0c00985
A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
- Jonathan M Ghergurovich, Juan C García-Cañaveras, Joshua Wang, …, Ulf H Beier, Hahn Kim, Joshua D Rabinowitz
- Nat Chem Biol, 10.1038/s41589-020-0533-x
A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism
- Junyoung O Park
- Li Chen
- June 13, 2019
- kedalionlabs.com
- Andrew F Schober, Andrew D Mathis, Christine Ingle, …, Ivan Junier, Olivier Rivoire, Kimberly A Reynolds
- Cell Rep, 10.1016/j.celrep.2019.05.030
The Tumor Metabolic Microenvironment: Lessons from Lactate
- Juan Carlos García-Cañaveras
- Li Chen
- June 8, 2019
- kedalionlabs.com
- Juan C García-Cañaveras, Li Chen, Joshua D Rabinowitz
- Cancer Res, 10.1158/0008-5472.can-18-3726
The metabolites NADP + and NADPH are the targets of the circadian protein Nocturnin (Curled)
- Li Chen
- June 1, 2019
- kedalionlabs.com
- Michael A Estrella, Jin Du, Li Chen, …, Paul Schedl, Joshua Rabinowitz, Alexei Korennykh
- Nat Commun, 10.1038/s41467-019-10125-z
Chemical Basis for Deuterium Labeling of Fat and NADPH
- Li Chen
- Ling Liu
- Zhaoyue Zhang
- September 16, 2017
- kedalionlabs.com
- Zhaoyue Zhang, Li Chen, Ling Liu, Xiaoyang Su, Joshua D Rabinowitz
- J Am Chem Soc, 10.1021/jacs.7b08012
An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate
- Li Chen
- Xin Teng
- August 12, 2017
- kedalionlabs.com
- Li Chen, Gregory S Ducker, Wenyun Lu, Xin Teng, Joshua D Rabinowitz
- Anal Bioanal Chem, 10.1007/s00216-017-0514-4
Photoaffinity labeling of transcription factors by DNA-templated crosslinking
- Li Chen
- July 15, 2017
- kedalionlabs.com
- Ying Liu, Wenlu Zheng, Wan Zhang, …, Xingshuo Chen, Haifeng Zheng, Xiaoyu Li
- None, 10.1039/c4sc01953a
Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors
- Li Chen
- Sheng Hui
- May 13, 2017
- kedalionlabs.com
- Wenyun Lu, Lin Wang, Li Chen, Sheng Hui, Joshua D Rabinowitz
- Antioxid Redox Signal, 10.1089/ars.2017.7014
Photoaffinity labeling of small-molecule-binding proteins by DNA-templated chemistry
- Li Chen
- June 19, 2013
- kedalionlabs.com
- Gang Li, Ying Liu, Yu Liu, …, Siyu Wu, Yang Liu, Xiaoyu Li
- Angew Chem Int Ed Engl, 10.1002/anie.201302161