
Academic lineage
NAD + precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury
- Karthikeyani Chellappa
- March 14, 2023
- kedalionlabs.com
- Tomohito Doke, Sarmistha Mukherjee, Dhanunjay Mukhi, …, Beishan Chen, Joseph A Baur, Katalin Susztak
- Nat Metab, 10.1038/s42255-023-00761-7
NAD precursors cycle between host tissues and the gut microbiome
- Connor Jankowski
- Karthikeyani Chellappa
- Wenyun Lu
- Xianfeng Zeng
- December 8, 2022
- kedalionlabs.com
- Karthikeyani Chellappa, Melanie R McReynolds, Wenyun Lu, …, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
- Cell Metab, 10.1016/j.cmet.2022.11.004
NAD + flux is maintained in aged mice despite lower tissue concentrations
- Connor Jankowski
- Karthikeyani Chellappa
- Li Chen
- Yihui Shen
- September 24, 2021
- kedalionlabs.com
- Melanie R McReynolds, Karthikeyani Chellappa, Eric Chiles, …, Xiaoyang Su, Joshua D Rabinowitz, Joseph A Baur
- Cell Syst, 10.1016/j.cels.2021.09.001
SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside
- Karthikeyani Chellappa
- March 10, 2021
- kedalionlabs.com
- Sarmistha Mukherjee, James Mo, Lauren M Paolella, …, Qiang Tong, Karthikeyani Chellappa, Joseph A Baur
- JCI Insight, 10.1172/jci.insight.147193
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD + and NMN levels
- Connor Jankowski
- Karthikeyani Chellappa
- Kelly A Hogan
- November 17, 2020
- kedalionlabs.com
- Claudia C S Chini, Thais R Peclat, Gina M Warner, …, Joshua D Rabinowitz, Joseph A Baur, Eduardo N Chini
- Nat Metab, 10.1038/s42255-020-00298-z
Rapamycin maintains NAD + /NADH redox homeostasis in muscle cells
- Karthikeyani Chellappa
- September 22, 2020
- kedalionlabs.com
- Zhigang Zhang, He N Xu, Siyu Li, …, Huaqing Zhao, Lin Z Li, Joseph A Baur
- Aging (Albany NY), 10.18632/aging.103954
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia
- Karthikeyani Chellappa
- February 8, 2020
- kedalionlabs.com
- Lauren M Paolella, Sarmistha Mukherjee, Cassie M Tran, …, Wenyun Lu, Karthikeyani Chellappa, Joseph A Baur
- Mol Metab, 10.1016/j.molmet.2019.12.003
Hypothalamic mTORC2 is essential for metabolic health and longevity
- Karthikeyani Chellappa
- August 3, 2019
- kedalionlabs.com
- Karthikeyani Chellappa, Jacqueline A Brinkman, Sarmistha Mukherjee, …, Georgios K Paschos, Joseph A Baur, Dudley W Lamming
- Aging Cell, 10.1111/acel.13014
Optical Redox Imaging of Fixed Unstained Muscle Slides Reveals Useful Biological Information
- Karthikeyani Chellappa
- April 13, 2019
- kedalionlabs.com
- He N Xu, Huaqing Zhao, Karthikeyani Chellappa, …, Shoko Nioka, Joseph A Baur, Lin Z Li
- Mol Imaging Biol, 10.1007/s11307-019-01348-z
Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
- Karthikeyani Chellappa
- Ling Liu
- June 13, 2018
- kedalionlabs.com
- Antonio Davila, Ling Liu, Karthikeyani Chellappa, …, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
- Elife, 10.7554/elife.33246
Quantitative Analysis of NAD Synthesis-Breakdown Fluxes
- Karthikeyani Chellappa
- Ling Liu
- Sheng Hui
- April 25, 2018
- kedalionlabs.com
- Ling Liu, Xiaoyang Su, William J Quinn, …, Timothy J Mitchison, Joseph A Baur, Joshua D Rabinowitz
- Cell Metab, 10.1016/j.cmet.2018.03.018
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration
- Karthikeyani Chellappa
- November 4, 2016
- kedalionlabs.com
- Sarmistha Mukherjee, Karthikeyani Chellappa, Andrea Moffitt, …, James G Davis, Beamon Agarwal, Joseph A Baur
- Hepatology, 10.1002/hep.28912
Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle
- Karthikeyani Chellappa
- Ling Liu
- August 11, 2016
- kedalionlabs.com
- David W Frederick, Emanuele Loro, Ling Liu, …, Joshua D Rabinowitz, Tejvir S Khurana, Joseph A Baur
- Cell Metab, 10.1016/j.cmet.2016.07.005