
Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging
- Joris Deelen
- April 28, 2023
- kedalionlabs.com
- Evgeny S Tiys, Saori Sakaue, Masato Akiyama, …, Peter K Joshi, James F Wilson, Yakov A Tsepilov
- Nat Aging, 10.1038/s43587-021-00159-8
Convergent genomics of longevity in rockfishes highlights the genetics of human life span variation
- Joris Deelen
- January 11, 2023
- kedalionlabs.com
- Stephen Treaster, Joris Deelen, Jacob M Daane, …, Joanne Murabito, David Karasik, Matthew P Harris
- Sci Adv, 10.1126/sciadv.add2743
Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS
- Joris Deelen
- Marian Beekman
- February 23, 2022
- kedalionlabs.com
- Paul J Hop, Ramona A J Zwamborn, Eilis Hannon, …, Philip Van Damme, Jonathan Mill, Jan H Veldink
- Sci Transl Med, 10.1126/scitranslmed.abj0264
Targeting multimorbidity: Using healthspan and lifespan to identify biomarkers of ageing that pinpoint shared disease mechanisms
- Joris Deelen
- May 9, 2021
- kedalionlabs.com
- Joris Deelen
- EBioMedicine, 10.1016/j.ebiom.2021.103364
From mutation to mechanism: deciphering the molecular function of genetic variants linked to human ageing
- Joris Deelen
- Maarouf Baghdadi
- March 10, 2021
- kedalionlabs.com
- Maarouf Baghdadi, Helena M Hinterding, Linda Partridge, Joris Deelen
- Brief Funct Genomics, 10.1093/bfgp/elab005
Genome-wide association study of circulating interleukin 6 levels identifies novel loci
- Joris Deelen
- January 31, 2021
- kedalionlabs.com
- Tarunveer S Ahluwalia, Bram P Prins, Mohammadreza Abdollahi, …, Bruce M Psaty, Harold Snieder, Behrooz Z Alizadeh
- Hum Mol Genet, 10.1093/hmg/ddab023
Correlation of the two most frequent HLA haplotypes in the Italian population to the differential regional incidence of Covid-19
- Joris Deelen
- September 16, 2020
- kedalionlabs.com
- Simona Pisanti, Joris Deelen, Anna Maria Gallina, …, Nicoletta Sacchi, Carmine Vecchione, Rosanna Martinelli
- J Transl Med, 10.1186/s12967-020-02515-5