Academic lineage
Video highlight
Exploring conditional gene essentiality through systems genetics approaches in yeast
- Núria Bosch-Guiteras, Jolanda van Leeuwen
- Curr Opin Genet Dev, 10.1016/j.gde.2022.101963
Predicting base editing outcomes using position-specific sequence determinants
- Ananth Pallaseni, Elin Madli Peets, Jonas Koeppel, …, Jolanda van Leeuwen, Felicity Allen, Leopold Parts
- Nucleic Acids Res, 10.1093/nar/gkac161
Chl1 helicase controls replication fork progression by regulating dNTP pools
- Amandine Batté, Sophie C van der Horst, Mireille Tittel-Elmer, …, Jolanda van Leeuwen, Andrei Chabes, Haico van Attikum
- Life Sci Alliance, 10.26508/lsa.202101153
Natural variants suppress mutations in hundreds of essential genes
- Leopold Parts, Amandine Batté, Maykel Lopes, …, Patrick Aloy, Gianni Liti, Jolanda van Leeuwen
- Mol Syst Biol, 10.15252/msb.202010138
Systematic analysis of bypass suppression of essential genes
- Jolanda van Leeuwen, Carles Pons, Guihong Tan, …, Patrick Aloy, Brenda J Andrews, Charles Boone
- Mol Syst Biol, 10.15252/msb.20209828
Exploring whole-genome duplicate gene retention with complex genetic interaction analysis
- Elena Kuzmin, Benjamin VanderSluis, Alex N Nguyen Ba, …, Chad L Myers, Brenda J Andrews, Charles Boone
- Science, 10.1126/science.aaz5667
Global Genetic Networks and the Genotype-to-Phenotype Relationship
- Michael Costanzo, Elena Kuzmin, Jolanda van Leeuwen, …, Jason Moffat, Charles Boone, Brenda Andrews
- Cell, 10.1016/j.cell.2019.01.033
Mapping a diversity of genetic interactions in yeast
- Jolanda van Leeuwen, Charles Boone, Brenda J Andrews
- None, 10.1016/j.coisb.2017.08.002
Genetic Network Complexity Shapes Background-Dependent Phenotypic Expression
- Jing Hou, Jolanda van Leeuwen, Brenda J Andrews, Charles Boone
- Trends Genet, 10.1016/j.tig.2018.05.006
Systematic analysis of complex genetic interactions
- Elena Kuzmin, Benjamin VanderSluis, Wen Wang, …, Brenda J Andrews, Charles Boone, Chad L Myers
- Science, 10.1126/science.aao1729
Yeast Aim21/Tda2 both regulates free actin by reducing barbed end assembly and forms a complex with Cap1/Cap2 to balance actin assembly between patches and cables
- Myungjoo Shin, Jolanda van Leeuwen, Charles Boone, Anthony Bretscher
- Mol Biol Cell, 10.1091/mbc.e17-10-0592
Functional annotation of chemical libraries across diverse biological processes
- Jeff S Piotrowski, Sheena C Li, Raamesh Deshpande, …, Minoru Yoshida, Chad L Myers, Charles Boone
- Nat Chem Biol, 10.1038/nchembio.2436
Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens
- Traver Hart, Amy Hin Yan Tong, Katie Chan, …, Charles Boone, Daniel Durocher, Jason Moffat
- G3 (Bethesda), 10.1534/g3.117.041277
Mechanisms of suppression: The wiring of genetic resilience
- Jolanda van Leeuwen, Carles Pons, Charles Boone, Brenda J Andrews
- Bioessays, 10.1002/bies.201700042
The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae
- Angelina Huseinovic, Jolanda S van Leeuwen, Tibor van Welsem, …, Nico P E Vermeulen, Jan M Kooter, J Chris Vos
- PLoS One, 10.1371/journal.pone.0173573
Exploring genetic suppression interactions on a global scale
- Jolanda van Leeuwen, Carles Pons, Joseph C Mellor, …, Brenda J Andrews, Frederick P Roth, Charles Boone
- Science, 10.1126/science.aag0839
A global genetic interaction network maps a wiring diagram of cellular function
- Michael Costanzo, Benjamin VanderSluis, Elizabeth N Koch, …, Chad L Myers, Brenda Andrews, Charles Boone
- Science, 10.1126/science.aaf1420
Construction of Multifragment Plasmids by Homologous Recombination in Yeast
- Jolanda van Leeuwen, Brenda Andrews, Charles Boone, Guihong Tan
- Cold Spring Harb Protoc, 10.1101/pdb.top084111