Academic lineage
Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking
- Lihong Liu, Ryan G Casner, Yicheng Guo, …, Jesse D Bloom, Lawrence Shapiro, David D Ho
- None, 10.1101/2023.04.08.536123
Evolution of the SARS-CoV-2 Mutational Spectrum
- Jesse D Bloom, Annabel C Beichman, Richard A Neher, …, Annabel C Beichman, Richard A Neher, Kelley Harris
- Mol Biol Evol, 10.1093/molbev/msad085
The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito
- Chelsea Cereghino, Ferdinand Roesch, Lucía Carrau, …, Maria-Carla Saleh, Marco Vignuzzi, James Weger-Lucarelli
- PLoS Pathog, 10.1371/journal.ppat.1010491
The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution
- Alief Moulana, Thomas Dupic, Angela M Phillips, …, Tyler N Starr, Jesse D Bloom, Michael M Desai
- Elife, 10.7554/elife.83442
Fitness effects of mutations to SARS-CoV-2 proteins
- Jesse D Bloom, Richard A Neher, Jesse D Bloom, …, Richard A Neher, Jesse D Bloom, Richard A Neher
- None, 10.1101/2023.01.30.526314
Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains
- Tyler N Starr, Allison J Greaney, Cameron M Stewart, …, William W Hannon, David Veesler, Jesse D Bloom
- PLoS Pathog, 10.1371/journal.ppat.1010951
Compensatory epistasis maintains ACE2 affinity in SARS-CoV-2 Omicron BA.1
- Alief Moulana, Thomas Dupic, Angela M Phillips, …, Tyler N Starr, Jesse D Bloom, Michael M Desai
- Nat Commun, 10.1038/s41467-022-34506-z
Computationally restoring the potency of a clinical antibody against SARS-CoV-2 Omicron subvariants
- Thomas A Desautels, Kathryn T Arrildt, Adam T Zemla, …, James E Crowe, Robert H Carnahan, Daniel M Faissol
- None, 10.1101/2022.10.21.513237
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
- Alexander A Cohen, Neeltje van Doremalen, Allison J Greaney, …, Jesse D Bloom, Vincent J Munster, Pamela J Bjorkman
- Science, 10.1126/science.abq0839
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
- Tyler N Starr, Allison J Greaney, William W Hannon, …, David Veesler, Gyorgy Snell, Jesse D Bloom
- Science, 10.1126/science.abo7896
Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein
- M Alejandra Tortorici, Alexandra C Walls, Anshu Joshi, …, Davide Corti, Jesse D Bloom, David Veesler
- Cell, 10.1016/j.cell.2022.05.019
Defining the risk of SARS-CoV-2 variants on immune protection
- Marciela M DeGrace, Elodie Ghedin, Matthew B Frieman, …, Michael S Diamond, Diane J Post, Mehul S Suthar
- Nature, 10.1038/s41586-022-04690-5
Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail
- Amin Addetia, Young-Jun Park, Tyler Starr, …, Davide Corti, Alexandra C Walls, David Veesler
- None, 10.1101/2022.01.21.477288
