Inducible CRISPRi-Based Operon Silencing and Selective in Trans Gene Complementation in Borrelia burgdorferi
- Bryan T Murphy, Jacob J Wiepen, Huan He, …, Jason M Peters, Brian Stevenson, Wolfram R Zückert
- J Bacteriol, 10.1128/jb.00468-22
Fatty Acid Synthesis Knockdown Promotes Biofilm Wrinkling and Inhibits Sporulation in Bacillus subtilis
- Heidi A Arjes, Haiwen Gui, Rachel Porter, …, Carol Gross, Daniel B Kearns, Kerwyn Casey Huang
- mBio, 10.1128/mbio.01388-22
Morphological and Transcriptional Responses to CRISPRi Knockdown of Essential Genes in Escherichia coli
- Melanie R Silvis, Manohary Rajendram, Handuo Shi, …, Horia Todor, Kerwyn Casey Huang, Carol A Gross
- mBio, 10.1128/mbio.02561-21
Inhibition of Isoleucyl-tRNA Synthetase by the Hybrid Antibiotic Thiomarinol
- Rachel A Johnson, Andrew N Chan, Ryan D Ward, …, Breanne M Hatfield, Jason M Peters, Bo Li
- J Am Chem Soc, 10.1021/jacs.1c02622
Chemical-genetic interrogation of RNA polymerase mutants reveals structure-function relationships and physiological tradeoffs
- Anthony L Shiver, Hendrik Osadnik, Jason M Peters, …, Robert Landick, Kerwyn Casey Huang, Carol A Gross
- Mol Cell, 10.1016/j.molcel.2021.04.027
Three-dimensional biofilm colony growth supports a mutualism involving matrix and nutrient sharing
- Heidi A Arjes, Lisa Willis, Haiwen Gui, …, Jason Peters, Carol Gross, Kerwyn Casey Huang
- Elife, 10.7554/elife.64145
Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis
- John S Hawkins, Melanie R Silvis, Byoung-Mo Koo, …, Jonathan S Weissman, Horia Todor, Carol A Gross
- Cell Syst, 10.1016/j.cels.2020.09.009
A High-Efficacy CRISPR Interference System for Gene Function Discovery in Zymomonas mobilis
- Amy B Banta, Amy L Enright, Cheta Siletti, Jason M Peters
- Appl Environ Microbiol, 10.1128/aem.01621-20
Modulating Pathogenesis with Mobile-CRISPRi
- Jiuxin Qu, Neha K Prasad, Michelle A Yu, …, Mark R Looney, Jason M Peters, Oren S Rosenberg
- J Bacteriol, 10.1128/jb.00304-19
Enabling genetic analysis of diverse bacteria with Mobile-CRISPRi
- Jason M Peters, Byoung-Mo Koo, Ramiro Patino, …, Alan D Grossman, Carol A Gross, Oren S Rosenberg
- Nat Microbiol, 10.1038/s41564-018-0327-z
Structure and Function of the Transmembrane Domain of NsaS, an Antibiotic Sensing Histidine Kinase in Staphylococcus aureus
- Manasi P Bhate, Thomas Lemmin, Georg Kuenze, …, Carol A Gross, Jens Meiler, William F DeGrado
- J Am Chem Soc, 10.1021/jacs.7b09670