Hepatocyte SREBP signaling mediates clock communication within the liver
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Maternal low-calorie sweetener consumption rewires hypothalamic melanocortin circuits via a gut microbial co-metabolite pathway
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Hyperactivation of YAP/TAZ Drives Alterations in Mesangial Cells through Stabilization of N-Myc in Diabetic Nephropathy
- Seunghyeok Choi, Seon Pyo Hong, Jung Hyun Bae, …, Kyung Pyo Kang, Hyuek Jong Lee, Gou Young Koh
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Metabolic flux between organs measured by arteriovenous metabolite gradients
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Dietary Fructose and Fructose-Induced Pathologies
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Glycerate from intestinal fructose metabolism induces islet cell damage and glucose intolerance
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Nasal ciliated cells are primary targets for SARS-CoV-2 replication in the early stage of COVID-19
- Ji Hoon Ahn, JungMo Kim, Seon Pyo Hong, …, Hosung Bae, Chang-Seop Lee, Gou Young Koh
- J Clin Invest, 10.1172/jci148517
Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi
- Seon Pyo Hong, Myung Jin Yang, Hyunsoo Cho, …, Kari Alitalo, Daesik Lim, Gou Young Koh
- Nat Commun, 10.1038/s41467-020-17886-y
YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells
- Sung Yong Choi, Hosung Bae, Sun-Hye Jeong, …, Joo-Hye Song, Dae-Sik Lim, Gou Young Koh
- Nat Commun, 10.1038/s41467-020-14293-1
Tie2 activation promotes choriocapillary regeneration for alleviating neovascular age-related macular degeneration
- Jaeryung Kim, Jang Ryul Park, Jeongwoon Choi, …, Hellmut G Augustin, Wang-Yuhl Oh, Gou Young Koh
- Sci Adv, 10.1126/sciadv.aau6732
Tumor metastasis to lymph nodes requires YAP-dependent metabolic adaptation
- Choong-Kun Lee, Seung-Hwan Jeong, Cholsoon Jang, …, Intae Park, Sang Kyum Kim, Gou Young Koh
- Science, 10.1126/science.aav0173