Effects of n-butanol production on metabolism and the photosystem in Synecococcus elongatus PCC 7942 based on metabolic flux and target proteome analyses
- Keisuke Wada, Kiyoka Uebayashi, Yoshihiro Toya, …, Eiichiro Fukusaki, James C Liao, Hiroshi Shimizu
- J Gen Appl Microbiol, 10.2323/jgam.2023.03.002
Functional evaluation of non-oxidative glycolysis in Escherichia coli in the stationary phase under microaerobic conditions
- Kenta Miyoshi, Ryutaro Kawai, Teppei Niide, …, Teppei Niide, Yoshihiro Toya, Hiroshi Shimizu
- J Biosci Bioeng, 10.1016/j.jbiosc.2023.01.002
Effect of light fluctuations on photosynthesis and metabolic flux in Synechocystis sp. PCC 6803
- Tatsumi Imada, Chiaki Yamamoto, Masakazu Toyoshima, …, Masakazu Toyoshima, Yoshihiro Toya, Hiroshi Shimizu
- Biotechnol Prog, 10.1002/btpr.3326
Conversion of Mevalonate to Isoprenol Using Light Energy in Escherichia coli without Consuming Sugars for ATP Supply
- Mikoto Sano, Ryo Tanaka, Kentaro Kamata, …, Kiyotaka Y Hara, Hiroshi Shimizu, Yoshihiro Toya
- ACS Synth Biol, 10.1021/acssynbio.2c00313
Logistic Regression-Guided Identification of Cofactor Specificity-Contributing Residues in Enzyme with Sequence Datasets Partitioned by Catalytic Properties
- Sou Sugiki, Teppei Niide, Yoshihiro Toya, …, Teppei Niide, Yoshihiro Toya, Hiroshi Shimizu
- ACS Synth Biol, 10.1021/acssynbio.2c00315
Metabolic pathway design for growth-associated phenylalanine production using synthetically designed mutualism
- Ryutaro Kawai, Yoshihiro Toya, Hiroshi Shimizu
- Bioprocess Biosyst Eng, 10.1007/s00449-022-02762-4
13 C metabolic flux analysis clarifies distinct metabolic phenotypes of cancer cell spheroid mimicking tumor hypoxia
- Shingo Noguchi, Kenichi Wakita, Fumio Matsuda, Hiroshi Shimizu
- Metab Eng, 10.1016/j.ymben.2022.07.008
Constitutive expression of the global regulator AbrB restores the growth defect of a genome-reduced Bacillus subtilis strain and improves its metabolite production
- Junya Yamamoto, Onuma Chumsakul, Yoshihiro Toya, …, Ken-Ichi Yoshida, Taku Oshima, Shu Ishikawa
- DNA Res, 10.1093/dnares/dsac015
Metabolic pathway engineering for the non-growth-associated succinate production in Escherichia coli based on flux solution space
- Yoshihiro Toya, Hiroshi Shimizu
- J Biosci Bioeng, 10.1016/j.jbiosc.2022.04.008
Optogenetic reprogramming of carbon metabolism using light-powering microbial proton pump systems
- Yoshihiro Toya, Yoko Hirono-Hara, Hidenobu Hirayama, …, Fumio Matsuda, Jun Ishii, Kiyotaka Y Hara
- Metab Eng, 10.1016/j.ymben.2022.03.012
mfapy: An open-source Python package for 13 C-based metabolic flux analysis
- Fumio Matsuda, Kousuke Maeda, Takeo Taniguchi, …, Futa Yatabe, Nobuyuki Okahashi, Hiroshi Shimizu
- Metab Eng, 10.1016/j.mec.2021.e00177
Proteome analysis of response to different spectral light irradiation in Synechocystis sp. PCC 6803
- Masakazu Toyoshima, Masumi Sakata, Yoshifumi Ueno, …, Fumio Matsuda, Seiji Akimoto, Hiroshi Shimizu
- J Proteomics, 10.1016/j.jprot.2021.104306
Soft-sensor development for monitoring the lysine fermentation process
- Kento Tokuyama, Yoshiki Shimodaira, Yohei Kodama, …, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
- J Biosci Bioeng, 10.1016/j.jbiosc.2021.04.002