Academic lineage
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
- Vanja Panic, Stephanie Pearson, James Banks, …, Gregory S Ducker, Jared Rutter, Claudio J Villanueva
- Elife, 10.7554/elife.52558
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia
- Juan C GarcÃa-Cañaveras, Olga Lancho, Gregory S Ducker, …, Hahn Kim, Daniel Herranz, Joshua D Rabinowitz
- Leukemia, 10.1038/s41375-020-0845-6
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
- Albert M Li, Gregory S Ducker, Yang Li, …, Joshua D Rabinowitz, Craig B Thompson, Jiangbin Ye
- Mol Cancer Res, 10.1158/1541-7786.mcr-19-0606
Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier
- Claire L Bensard, Dona R Wisidagama, Kristofor A Olson, …, Gregory S Ducker, Carl S Thummel, Jared Rutter
- Cell Metab, 10.1016/j.cmet.2019.11.002
A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors
- Chester E Chamberlain, Michael S German, Katherine Yang, …, Danny Lee, Yucheng Wang, Eric K Nakakura
- Mol Cancer Ther, 10.1158/1535-7163.mct-17-1204
5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination
- Lance H Rodan, Wanshu Qi, Gregory S Ducker, …, Joshua D Rabinowitz, Irina Anselm, Gerard T Berry
- Mol Genet Metab, 10.1016/j.ymgme.2018.06.006
Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy
- Olga Ksionda, Marsilius Mues, Anica M Wandler, …, Kevin Shannon, Kevan M Shokat, Jeroen P Roose
- PLoS One, 10.1371/journal.pone.0193849
Mitochondrial translation requires folate-dependent tRNA methylation
- Raphael J Morscher, Gregory S Ducker, Sophia Hsin-Jung Li, …, Zemer Gitai, Wolfgang Sperl, Joshua D Rabinowitz
- Nature, 10.1038/nature25460