Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics
- Brandon Ho, Ethan J Sanford, Raphael Loll-Krippleber, …, Nikko P Torres, Marcus B Smolka, Grant W Brown
- Elife, 10.7554/elife.82483
Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol
- Raphael Loll-Krippleber, Victoria A Sajtovich, Michael W Ferguson, …, Peter J Roy, Haley D M Wyatt, Grant W Brown
- Microb Cell Fact, 10.1186/s12934-022-02007-9
Distinct elongation stalls during translation are linked with distinct pathways for mRNA degradation
- Anthony J Veltri, Karole N D’Orazio, Laura N Lessen, Raphael Loll-Krippleber, Grant W Brown, Rachel Green
- Elife, 10.7554/elife.76038
Complex mutation profiles in mismatch repair and ribonucleotide reductase mutants reveal novel repair substrate specificity of MutS homolog (MSH) complexes
- Natalie A Lamb, Jonathan E Bard, Raphael Loll-Krippleber, …, Raphael Loll-Krippleber, Grant W Brown, Jennifer A Surtees
- Genetics, 10.1093/genetics/iyac092
Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG
- Matthew D Berg, Yanrui Zhu, Raphaël Loll-Krippleber, …, Judit Villén, Grant W Brown, Christopher J Brandl
- G3 (Bethesda), 10.1093/g3journal/jkac125
Yeast goes viral: probing SARS-CoV-2 biology using S. cerevisiae
- Brandon Ho, Raphael Loll-Krippleber, Grant W Brown
- None, 10.15698/mic2022.04.774
Author Correction: Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma
- Lukas Tamayo-Orrego, David Gallo, Frédéric Racicot, …, Andrew P Jackson, Grant W Brown, Frédéric Charron
- Nat Cancer, 10.1038/s43018-021-00205-9
LSD1 is required for euchromatic origin firing and replication timing
- Yue Wang, Yunchao Huang, Edith Cheng, …, Grant W Brown, Xiaohan Yang, Yongfeng Shang
- Signal Transduct Target Ther, 10.1038/s41392-022-00927-x
High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds
- Shinsuke Ohnuki, Itsuki Ogawa, Kaori Itto-Nakama, …, Grant W Brown, John Ralph, Yoshikazu Ohya
- NPJ Syst Biol Appl, 10.1038/s41540-022-00212-1
Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes
- Jessel Ayra-Plasencia, Cristina Ramos-Pérez, Silvia Santana-Sosa, …, Grant W Brown, Michael Lisby, Félix MachÃn
- Sci Rep, 10.1038/s41598-021-93875-5
Setting molecular traps in yeast for identification of anticancer drug targets
- Grant W Brown, Brenda Andrews
- Proc Natl Acad Sci U S A, 10.1073/pnas.2105547118
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors
- Parasvi S Patel, Karan Joshua Abraham, Kiran Kumar Naidu Guturi, …, Karim Mekhail, Anne Hakem, Razqallah Hakem
- J Clin Invest, 10.1172/jci140105