Extracellular vesicles of the Gram-positive gut symbiont Bifidobacterium longum induce immune-modulatory, anti-inflammatory effects
- Noa Mandelbaum, Lihan Zhang, Shaqed Carasso, …, Yeshayahu Talmon, Emily P Balskus, Naama Geva-Zatorsky
- NPJ Biofilms Microbiomes, 10.1038/s41522-023-00400-9
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease
- Raaj S Mehta, Jared R Mayers, Yancong Zhang, …, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
- Nat Med, 10.1038/s41591-023-02217-7
Elucidating the Chemistry and Biology of the Human Microbiome
- Emily P Balskus, Emily P Balskus, Emily P Balskus
- Biochemistry, 10.1021/acs.biochem.2c00652
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators
- Xueyang Dong, Ben G H Guthrie, Margaret Alexander, …, Nathaniel R Glasser, Peter J Turnbaugh, Emily P Balskus
- Nat Commun, 10.1038/s41467-022-33576-3
A small molecule inhibitor prevents gut bacterial genotoxin production
- Matthew R Volpe, José A Velilla, Martin Daniel-Ivad, …, Silvia Balbo, Rachelle Gaudet, Emily P Balskus
- Nat Chem Biol, 10.1038/s41589-022-01147-8
Structural basis of colibactin activation by the ClbP peptidase
- José A Velilla, Matthew R Volpe, Grace E Kenney, …, Richard M Walsh, Emily P Balskus, Rachelle Gaudet
- Nat Chem Biol, 10.1038/s41589-022-01142-z
Biosynthesis of the Unusual Carbon Skeleton of Nocuolin A
- Teresa P Martins, Nathaniel R Glasser, Duncan J Kountz, Paulo Oliveira, Emily P Balskus, Pedro N Leão
- ACS Chem Biol, 10.1021/acschembio.2c00464
Mechanistic Studies of a Skatole-Forming Glycyl Radical Enzyme Suggest Reaction Initiation via Hydrogen Atom Transfer
- Beverly Fu, Azadeh Nazemi, Benjamin J Levin, Zhongyue Yang, Heather J Kulik, Emily P Balskus
- J Am Chem Soc, 10.1021/jacs.1c13580
Emerging Chemical Diversity and Potential Applications of Enzymes in the DMSO Reductase Superfamily
- Chi Chip Le, Minwoo Bae, Sina Kiamehr, Emily P Balskus
- Annu Rev Biochem, 10.1146/annurev-biochem-032620-110804