Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-batch production
- Bassem Ben Yahia, Laetitia Malphettes, Elmar Heinzle
- Metab Eng, 10.1016/j.ymben.2021.04.004
Metabolic switches from quiescence to growth in synchronized Saccharomyces cerevisiae
- Jinrui Zhang, Karla Martinez-Gomez, Elmar Heinzle, Sebastian Aljoscha Wahl
- Metabolomics, 10.1007/s11306-019-1584-4
Network design and analysis for multi-enzyme biocatalysis
- Lisa Katharina BlaĂ, Christian Weyler, Elmar Heinzle
- BMC Bioinformatics, 10.1186/s12859-017-1773-y
Hepatocytes of Wistar and Sprague Dawley rats differ significantly in their central metabolism
- Richa Garg, Elmar Heinzle, Fozia Noor
- J Cell Biochem, 10.1002/jcb.26255
Proteomic Characterization of Primary Mouse Hepatocytes in Collagen Monolayer and Sandwich Culture
- Malina Orsini, Saskia Sperber, Fozia Noor, …, Rabea A Hall, Frank Lammert, Elmar Heinzle
- J Cell Biochem, 10.1002/jcb.26202
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology
- Clemens Wittwehr, Hristo Aladjov, Gerald Ankley, …, Dan Villeneuve, Katrina M Waters, Maurice Whelan
- Toxicol Sci, 10.1093/toxsci/kfw207
Synthesis of natural variants and synthetic derivatives of the cyclic nonribosomal peptide luminmide in permeabilized E. coli Nissle and product formation kinetics
- Christian Weyler, Elmar Heinzle
- Appl Microbiol Biotechnol, 10.1007/s00253-016-7770-7
Comparative Proteome Analysis in Schizosaccharomyces pombe Identifies Metabolic Targets to Improve Protein Production and Secretion
- Chien-Wen Hung, Tobias Klein, Liam Cassidy, …, Elmar Heinzle, Konstantin Schneider, Andreas Tholey
- Mol Cell Proteomics, 10.1074/mcp.m115.051474
Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase
- Christian Weyler, Matthias Bureik, Elmar Heinzle
- Biotechnol Lett, 10.1007/s10529-015-1995-x
In Silico Modeling for the Prediction of Dose and Pathway-Related Adverse Effects in Humans From In Vitro Repeated-Dose Studies
- Sebastian Klein, Silvia Maggioni, Joachim Bucher, …, Klaus Mauch, Elmar Heinzle, Fozia Noor
- Toxicol Sci, 10.1093/toxsci/kfv218
Identification of active elementary flux modes in mitochondria using selectively permeabilized CHO cells
- Averina Nicolae, Judith Wahrheit, Yannic Nonnenmacher, Christian Weyler, Elmar Heinzle
- Metab Eng, 10.1016/j.ymben.2015.09.014