Hepatocyte SREBP signaling mediates clock communication within the liver
- Dongyin Guan, Hosung Bae, Dishu Zhou, …, Bishuang Cai, Cholsoon Jang, Mitchell A Lazar
- J Clin Invest, 10.1172/jci163018
Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis
- Yang Xiao, Kirill Batmanov, Wenxiang Hu, …, Yifan Liu, David A Hill, Mitchell A Lazar
- Sci Transl Med, 10.1126/scitranslmed.adc9653
In silico integrative analysis of multi-omics reveals regulatory layers for diurnal gene expression in mouse liver
- Chunjie Jiang, Panpan Liu, Cam Mong La, Dongyin Guan
- Front Endocrinol (Lausanne), 10.3389/fendo.2022.955070
Circadian Regulation of Gene Expression and Metabolism in the Liver
- Dongyin Guan, Mitchell A Lazar, Dongyin Guan, Mitchell A Lazar
- Semin Liver Dis, 10.1055/a-1792-4240
Interconnections between circadian clocks and metabolism
- Dongyin Guan, Mitchell A Lazar
- J Clin Invest, 10.1172/jci148278
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids
- Wenxiang Hu, Chunjie Jiang, Mindy Kim, …, Ching-Hon Pui, Mary V Relling, Mitchell A Lazar
- Cell Metab, 10.1016/j.cmet.2021.06.004
Using GRO-Seq to Measure Circadian Transcription and Discover Circadian Enhancers
- Bin Fang, Dongyin Guan, Mitchell A Lazar
- Methods Mol Biol, 10.1007/978-1-0716-0381-9_10
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types
- Dongyin Guan, Ying Xiong, Trang Minh Trinh, …, Cholsoon Jang, Joshua D Rabinowitz, Mitchell A Lazar
- Science, 10.1126/science.aba8984
Shining light on dark matter in the genome
- Dongyin Guan, Mitchell A Lazar
- Proc Natl Acad Sci U S A, 10.1073/pnas.1918894116
Patient Adipose Stem Cell-Derived Adipocytes Reveal Genetic Variation that Predicts Antidiabetic Drug Response
- Wenxiang Hu, Chunjie Jiang, Dongyin Guan, …, Weiping Jia, Raymond E Soccio, Mitchell A Lazar
- Cell Stem Cell, 10.1016/j.stem.2018.11.018
Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes
- Dongyin Guan, Ying Xiong, Patricia C Borck, …, Harry Ischiropoulos, Joshua D Rabinowitz, Mitchell A Lazar
- Cell, 10.1016/j.cell.2018.06.031