Scholar: David A Guertin

David A Guertin

Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis

  • Grace Park, John A Haley, Johnny Le, …, Chinmay M Trivedi, Cholsoon Jang, David A Guertin
  • Nat Metab, 10.1038/s42255-023-00825-8
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Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1

  • Amelia K Luciano, Ekaterina D Korobkina, Scott P Lyons, …, Su Myung Jung, Arminja N Kettenbach, David A Guertin
  • J Biol Chem, 10.1016/j.jbc.2022.102379
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Integrating adipocyte insulin signaling and metabolism in the multi-omics era

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Stable Isotope Tracing and Metabolomics to Study In Vivo Brown Adipose Tissue Metabolic Fluxes

  • Su Myung Jung, Johnny Le, Will G Doxsey, …, Grace Park, David A Guertin, Cholsoon Jang
  • Methods Mol Biol, 10.1007/978-1-0716-2087-8_8
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Akt Is S-Palmitoylated: A New Layer of Regulation for Akt

  • Matías Blaustein, Estefanía Piegari, Camila Martínez Calejman, …, F Gisou van der Goot, María Martha Corvi, Alejandro Colman-Lerner
  • None, 10.3389/fcell.2021.626404
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The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

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Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT Signaling

  • Samuel W Entwisle, Camila Martinez Calejman, Anthony S Valente, …, Chien-Min Hung, David A Guertin, Judit Villén
  • Mol Cell Proteomics, 10.1074/mcp.ra120.001946
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mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis

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De Novo Lipogenesis as a Source of Second Messengers in Adipocytes

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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

  • Su Myung Jung, Chien-Min Hung, Samuel R Hildebrand, …, Raul Mostoslavsky, Christian M Metallo, David A Guertin
  • Mol Cell, 10.1016/j.molcel.2019.07.023
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mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis

  • Nuria Martinez, Catherine Y Cheng, Natkunam Ketheesan, …, David A Guertin, Amit Singhal, Hardy Kornfeld
  • EBioMedicine, 10.1016/j.ebiom.2019.06.052
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Spatiotemporal structure of cell fate decisions in murine neural crest

  • Ruslan Soldatov, Marketa Kaucka, Maria Eleni Kastriti, …, Kaj Fried, Peter V Kharchenko, Igor Adameyko
  • Science, 10.1126/science.aas9536
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Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

  • Sully Fernandez, John M Viola, AnnMarie Torres, …, Nathaniel W Snyder, Christian M Metallo, Kathryn E Wellen
  • Cell Rep, 10.1016/j.celrep.2019.04.112
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Brown fat organogenesis and maintenance requires AKT1 and AKT2

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