Slow TCA flux and ATP production in primary solid tumours but not metastases
- Caroline R Bartman, Daniel R Weilandt, Yihui Shen, …, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
- Nature, 10.1038/s41586-022-05661-6
Forever young: Sphk2 in HSCs, when less is more
- Victoria da Silva-Diz, Daniel Herranz, Victoria da Silva-Diz, Daniel Herranz
- Blood, 10.1182/blood.2022017932
Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia
- Natalia Baran, Alessia Lodi, Yogesh Dhungana, …, Stefano Tiziani, Trang Hoang, Marina Konopleva
- Nat Commun, 10.1038/s41467-022-30396-3
A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia
- Victoria da Silva-Diz, Bin Cao, Olga Lancho, …, Xiaoyang Su, Shengkan Jin, Daniel Herranz
- Blood, 10.1182/blood.2020008955
Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia
- Huizhong Xiong, Maicol Mancini, Michael Gobert, …, Daniel Herranz, Juan J Lafaille, Antonio Maraver
- Theranostics, 10.7150/thno.48067
SHMT inhibition is effective and synergizes with methotrexate in T-cell acute lymphoblastic leukemia
- Juan C GarcÃa-Cañaveras, Olga Lancho, Gregory S Ducker, …, Hahn Kim, Daniel Herranz, Joshua D Rabinowitz
- Leukemia, 10.1038/s41375-020-0845-6
The MYC Enhancer-ome: Long-Range Transcriptional Regulation of MYC in Cancer
- Olga Lancho, Daniel Herranz
- Trends Cancer, 10.1016/j.trecan.2018.10.003