Academic lineage
On the Origins of Enzymes: Phosphate-Binding Polypeptides Mediate Phosphoryl Transfer to Synthesize Adenosine Triphosphate
- Pratik Vyas, Sergey Malitsky, Maxim Itkin, …, Sergey Malitsky, Maxim Itkin, Dan S Tawfik
- J Am Chem Soc, 10.1021/jacs.2c08636
Correction to “Peptide-RNA Coacervates as a Cradle for the Evolution of Folded Domains”
- Manas Seal, Orit Weil-Ktorza, Dragana Despotović, …, Norman Metanis, Liam M Longo, Daniella Goldfarb
- J Am Chem Soc, 10.1021/jacs.2c11057
Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin
- Rosario Valenti, Jagoda Jabłońska, Dan S Tawfik
- Protein Sci, 10.1002/pro.4423
How gene duplication diversifies the landscape of protein oligomeric state and function
- Saurav Mallik, Dan S Tawfik, Emmanuel D Levy
- Curr Opin Genet Dev, 10.1016/j.gde.2022.101966
Utilization of diverse organophosphorus pollutants by marine bacteria
- Dragana Despotović, Einav Aharon, Olena Trofimyuk, …, Liam M Longo, Einat Segev, Dan S Tawfik
- Proc Natl Acad Sci U S A, 10.1073/pnas.2203604119
Uniform binding and negative catalysis at the origin of enzymes
- Elad Noor, Avi I Flamholz, Vijay Jayaraman, …, Wayne M Patrick, Ita Gruic-Sovulj, Dan S Tawfik
- Protein Sci, 10.1002/pro.4381
Innovation and tinkering in the evolution of oxidases
- Jagoda Jabłońska, Dan S Tawfik
- Protein Sci, 10.1002/pro.4310
Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance
- Kaitlyn Tsai, Vanja Stojković, Lianet Noda-Garcia, …, James S Fraser, Dan S Tawfik, Danica Galonić Fujimori
- Elife, 10.7554/elife.70017
The evolutionary history of the HUP domain
- Ita Gruic-Sovulj, Liam M Longo, Jagoda Jabłońska, Dan S Tawfik
- Crit Rev Biochem Mol Biol, 10.1080/10409238.2021.1957764
On the evolution of chaperones and cochaperones and the expansion of proteomes across the Tree of Life
- Mathieu E Rebeaud, Saurav Mallik, Pierre Goloubinoff, Dan S Tawfik
- Proc Natl Acad Sci U S A, 10.1073/pnas.2020885118
The evolution of oxygen-utilizing enzymes suggests early biosphere oxygenation
- Jagoda Jabłońska, Jagoda Jabłońska, Jagoda Jabłońska, Dan S Tawfik
- Nat Ecol Evol, 10.1038/s41559-020-01386-9
Enzyme evolution in natural products biosynthesis: target- or diversity-oriented?
- Lianet Noda-Garcia, Dan S Tawfik
- Curr Opin Chem Biol, 10.1016/j.cbpa.2020.05.011
Short and simple sequences favored the emergence of N-helix phospho-ligand binding sites in the first enzymes
- Liam M Longo, Dušan Petrović, Shina Caroline Lynn Kamerlin, Dan S Tawfik
- Proc Natl Acad Sci U S A, 10.1073/pnas.1911742117
On the Mechanism and Origin of Isoleucyl-tRNA Synthetase Editing against Norvaline
- Mirna Bilus, Maja Semanjski, Marko Mocibob, …, Agnes Toth-Petroczy, Boris Macek, Ita Gruic-Sovulj
- J Mol Biol, 10.1016/j.jmb.2019.01.029
The Limited Information Capacity of Cross-Reactive Sensors Drives the Evolutionary Expansion of Signaling
- Michał Komorowski, Dan S Tawfik
- Cell Syst, 10.1016/j.cels.2018.12.006
Simple yet functional phosphate-loop proteins
- Maria Luisa Romero Romero, Fan Yang, Yu-Ru Lin, …, David Baker, Gabriele Varani, Dan S Tawfik
- Proc Natl Acad Sci U S A, 10.1073/pnas.1812400115
Publisher Correction: Evolution of chalcone isomerase from a noncatalytic ancestor
- Miriam Kaltenbach, Jason R Burke, Mirco Dindo, …, Shina C L Kamerlin, Joseph P Noel, Dan S Tawfik
- Nat Chem Biol, 10.1038/s41589-018-0079-3
