Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens
- Maša Sterle, Martina Durcik, Clare E M Stevenson, …, Tihomir Tomašič, Andrej Emanuel Cotman, Anamarija Zega
- None, 10.1021/acsomega.3c01930
The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence
- Pramod K Jangir, Lois Ogunlana, Petra Szili, …, Csaba Pál, Timothy R Walsh, Craig R MacLean
- Elife, 10.7554/elife.84395
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus
- Martina Durcik, Andrej Emanuel Cotman, Žan Toplak, …, Csaba Pal, Tihomir Tomašič, Lucija Peterlin Mašič
- J Med Chem, 10.1021/acs.jmedchem.2c01905
Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains
- Gábor Apjok, Mónika Számel, Chryso Christodoulou, …, Balázs Papp, Csaba Pál, Bálint Kintses
- Nat Microbiol, 10.1038/s41564-023-01320-2
Plasticity and Stereotypic Rewiring of the Transcriptome Upon Bacterial Evolution of Antibiotic Resistance
- Gábor Grézal, Réka Spohn, Orsolya Méhi, …, István Nagy, Csaba Pál, Balázs Papp
- Mol Biol Evol, 10.1093/molbev/msad020
Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast
- Zoltán Farkas, Károly Kovács, Zsuzsa Sarkadi, …, Péter Horváth, Csaba Pál, Balázs Papp
- Nat Ecol Evol, 10.1038/s41559-022-01730-1
Proteome-wide landscape of solubility limits in a bacterial cell
- Ádám Györkei, Lejla Daruka, Dávid Balogh, …, Csaba Pál, Bálint Kintses, Balázs Papp
- Sci Rep, 10.1038/s41598-022-10427-1
Rationally designed foldameric adjuvants enhance antibiotic efficacy via promoting membrane hyperpolarization
- Kaushik Nath Bhaumik, Anasztázia Hetényi, Gábor Olajos, …, Diána Kata, Csaba Pál, Tamás A Martinek
- None, 10.1039/d1me00118c
Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity
- Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, …, Lajos Kemény, Balázs Papp, Csaba Pál
- Nat Cancer, 10.1038/s43018-021-00226-4
ssDNA recombineering boosts in vivo evolution of nanobodies displayed on bacterial surfaces
- Yamal Al-Ramahi, Akos Nyerges, Yago Margolles, …, Csaba Pál, Luis Ángel Fernández, Víctor de Lorenzo
- Commun Biol, 10.1038/s42003-021-02702-0
Corrigendum to: Limited evolutionary conservation of multidrug resistance and collateral sensitivity
- Gábor Apjok, Gábor Boross, Ákos Nyerges, …, Balázs Papp, Csaba Pál, Bálint Csörgő
- Mol Biol Evol, 10.1093/molbev/msab116
New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens
- Martina Durcik, Ákos Nyerges, Žiga Skok, …, Danijel Kikelj, Lucija Peterlin Mašič, Tihomir Tomašič
- Eur J Med Chem, 10.1016/j.ejmech.2021.113200
Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation
- Martina Durcik, Žiga Skok, Janez Ilaš, …, Csaba Pál, Lucija Peterlin Mašič, Tihomir Tomašič
- None, 10.3390/pharmaceutics13010006
Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations
- Károly Kovács, Zoltán Farkas, Djordje Bajić, …, Frank C P Holstege, Csaba Pál, Balázs Papp
- Mol Biol Evol, 10.1093/molbev/msaa280