Activating mTOR Mutations Are Detrimental in Nutrient-Poor Conditions
- Agata A Bielska, Caitlin F Harrigan, Yeon Ju Kyung, …, Quaid Morris, Wilhelm Palm, Craig B Thompson
- Cancer Res, 10.1158/0008-5472.can-22-0121
A mitochondrial long-chain fatty acid oxidation defect leads to transfer RNA uncharging and activation of the integrated stress response in the mouse heart
- Pablo Ranea-Robles, Natalya N Pavlova, Aaron Bender, …, Carmen Argmann, Michelle Puchowicz, Sander M Houten
- Cardiovasc Res, 10.1093/cvr/cvac050
Ketohexokinase-mediated fructose metabolism is lost in hepatocellular carcinoma and can be leveraged for metabolic imaging
- Sui Seng Tee, Nathaniel Kim, Quinlan Cullen, …, Craig B Thompson, Andrea Schietinger, Kayvan R Keshari
- Sci Adv, 10.1126/sciadv.abm7985
The hallmarks of cancer metabolism: Still emerging
- Natalya N Pavlova, Jiajun Zhu, Craig B Thompson, Natalya N Pavlova, Jiajun Zhu, Craig B Thompson
- Cell Metab, 10.1016/j.cmet.2022.01.007
Leucine retention in lysosomes is regulated by starvation
- Urmi Bandyopadhyay, Pavlina Todorova, Natalya N Pavlova, …, Craig B Thompson, Lydia W S Finley, Michael Overholtzer
- Proc Natl Acad Sci U S A, 10.1073/pnas.2114912119
Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism
- Albert M Li, Gregory S Ducker, Yang Li, …, Joshua D Rabinowitz, Craig B Thompson, Jiangbin Ye
- Mol Cancer Res, 10.1158/1541-7786.mcr-19-0606
