Academic lineage
- Joshua D Rabinowitz - Postdoctoral Associate
Slow TCA flux and ATP production in primary solid tumours but not metastases
- Caroline R Bartman, Daniel R Weilandt, Yihui Shen, …, Jessie Yanxiang Guo, Yibin Kang, Joshua D Rabinowitz
- Nature, 10.1038/s41586-022-05661-6
NAD precursors cycle between host tissues and the gut microbiome
- Karthikeyani Chellappa, Melanie R McReynolds, Wenyun Lu, …, Marie E Migaud, Joshua D Rabinowitz, Joseph A Baur
- Cell Metab, 10.1016/j.cmet.2022.11.004
Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate
- Connor S R Jankowski, Joshua D Rabinowitz, Connor S R Jankowski, Joshua D Rabinowitz
- Cancer Res, 10.1158/0008-5472.can-22-0408
An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice
- Kristine A Tsantilas, Whitney M Cleghorn, Celia M Bisbach, …, David J Marcinek, Peter S Rabinovitch, James B Hurley
- Invest Ophthalmol Vis Sci, 10.1167/iovs.62.14.20
GCN2 adapts protein synthesis to scavenging-dependent growth
- Michel Nofal, Tim Wang, Lifeng Yang, …, Martin Wühr, David M Sabatini, Joshua D Rabinowitz
- Cell Syst, 10.1016/j.cels.2021.09.014
NAD + flux is maintained in aged mice despite lower tissue concentrations
- Melanie R McReynolds, Karthikeyani Chellappa, Eric Chiles, …, Xiaoyang Su, Joshua D Rabinowitz, Joseph A Baur
- Cell Syst, 10.1016/j.cels.2021.09.001
The human cytomegalovirus protein pUL13 targets mitochondrial cristae architecture to increase cellular respiration during infection
- Cora N Betsinger, Connor S R Jankowski, William A Hofstadter, …, Clayton J Otter, Pierre M Jean Beltran, Ileana M Cristea
- Proc Natl Acad Sci U S A, 10.1073/pnas.2101675118
The Source of Glycolytic Intermediates in Mammalian Tissues
- Tara TeSlaa, Caroline R Bartman, Connor S R Jankowski, …, Wenyun Lu, Sheng Hui, Joshua D Rabinowitz
- Cell Metab, 10.1016/j.cmet.2020.12.020
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD + and NMN levels
- Claudia C S Chini, Thais R Peclat, Gina M Warner, …, Joshua D Rabinowitz, Joseph A Baur, Eduardo N Chini
- Nat Metab, 10.1038/s42255-020-00298-z
Pyruvate kinase M2 regulates photoreceptor structure, function, and viability
- Ammaji Rajala, Yuhong Wang, Richard S Brush, …, James B Hurley, Robert E Anderson, Raju V S Rajala
- Cell Death Dis, 10.1038/s41419-018-0296-4
Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye
- Mark A Kanow, Michelle M Giarmarco, Connor Sr Jankowski, …, Martin Sadilek, Jennifer R Chao, James B Hurley
- Elife, 10.7554/elife.28899
Human retinal pigment epithelial cells prefer proline as a nutrient and transport metabolic intermediates to the retinal side
- Jennifer R Chao, Kaitlen Knight, Abbi L Engel, …, Daniel Raftery, James B Hurley, Jianhai Du
- J Biol Chem, 10.1074/jbc.m117.788422
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium
- Jianhai Du, Aya Yanagida, Kaitlen Knight, …, Aravind Ramakrishnan, James B Hurley, Jennifer R Chao
- Proc Natl Acad Sci U S A, 10.1073/pnas.1604572113