Reduced methionine synthase expression results in uracil accumulation in mitochondrial DNA and impaired oxidative capacity
- Katarina E Heyden, Joanna L Fiddler, Yuwen Xiu, …, Christian M Metallo, Marie A Caudill, Martha S Field
- None, 10.1093/pnasnexus/pgad105
Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease
- Courtney R Green, Roberto Bonelli, Brendan R E Ansell, …, Martin Friedlander, Christian M Metallo, Marin L Gantner
- Mol Metab, 10.1016/j.molmet.2023.101716
Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism
- Greg W Trieger, Ariane R Pessentheiner, Sean C Purcell, …, Christian M Metallo, Kamil Godula, Philip L S M Gordts
- J Biol Chem, 10.1016/j.jbc.2023.104611
Publisher Correction: Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
- Hua Su, Fei Yang, Rao Fu, …, David Brenner, Beicheng Sun, Michael Karin
- Nature, 10.1038/s41586-023-05920-0
Nutrient regulation of the islet epigenome controls adaptive insulin secretion
- Matthew Wortham, Fenfen Liu, Austin R Harrington, …, Kyle J Gaulton, Christian M Metallo, Maike Sander
- J Clin Invest, 10.1172/jci165208
Collagenolysis-dependent DDR1 signalling dictates pancreatic cancer outcome
- Hua Su, Fei Yang, Rao Fu, …, David Brenner, Beicheng Sun, Michael Karin
- Nature, 10.1038/s41586-022-05169-z
1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells
- Thekla Cordes, Ramya S Kuna, Grace H McGregor, …, Jivani Gengatharan, Thangaselvam Muthusamy, Christian M Metallo
- J Lipid Res, 10.1016/j.jlr.2022.100281
Acetate reprograms gut microbiota during alcohol consumption
- Cameron Martino, Livia S Zaramela, Bei Gao, …, Christian M Metallo, Bernd Schnabl, Karsten Zengler
- Nat Commun, 10.1038/s41467-022-31973-2
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy
- Isaac Perea-Gil, Timon Seeger, Arne A N Bruyneel, …, Christian M Metallo, Mark Mercola, Ioannis Karakikes
- Eur Heart J, 10.1093/eurheartj/ehac305
The lactate-NAD + axis activates cancer-associated fibroblasts by downregulating p62
- Juan F Linares, Tania Cid-Diaz, Angeles Duran, …, Christian M Metallo, Jorge Moscat, Maria T Diaz-Meco
- Cell Rep, 10.1016/j.celrep.2022.110792
Daily running enhances molecular and physiological circadian rhythms in skeletal muscle
- Nuria Casanova-Vallve, Drew Duglan, Megan E Vaughan, …, Christian M Metallo, Ronald M Evans, Katja A Lamia
- Mol Metab, 10.1016/j.molmet.2022.101504