Misregulation of cell cycle dependent methylation of budding yeast CENP-A contributes to chromosomal instability
- Prashant K Mishra, Wei-Chun Au, Pedro G Castineira, …, Kerry S Bloom, Peter H Thorpe, Munira A Basrai
- Mol Biol Cell, 10.1091/mbc.e23-03-0108
Reproducibility metrics for context-specific CRISPR screens
- Maximilian Billmann, Henry N Ward, Michael Aregger, …, Charles Boone, Jason Moffat, Chad L Myers
- Cell Syst, 10.1016/j.cels.2023.04.003
The proteomic landscape of genome-wide genetic perturbations
- Christoph B Messner, Vadim Demichev, Julia Muenzner, …, Charles Boone, Georg Kustatscher, Markus Ralser
- Cell, 10.1016/j.cell.2023.03.026
PIFiA: Self-supervised Approach for Protein Functional Annotation from Single-Cell Imaging Data
- Anastasia Razdaibiedina, Alexander Brechalov, Helena Friesen, …, Charles Boone, Jimmy Ba, Brenda Andrews
- None, 10.1101/2023.02.24.529975
Context-dependent regulation of ferroptosis sensitivity
- Leslie Magtanong, Grace D Mueller, Kevin J Williams, …, James A Olzmann, Steven J Bensinger, Scott J Dixon
- Cell Chem Biol, 10.1016/j.chembiol.2022.08.008
Repression of essential cell cycle genes increases cellular fitness
- Michelle M Conti, Julie M Ghizzoni, Ana Gil-Bona, …, Charles Boone, Brenda J Andrews, Jennifer A Benanti
- PLoS Genet, 10.1371/journal.pgen.1010349
Author Correction: Chemical genomics with pyrvinium identifies C1orf115 as a regulator of drug efflux
- Sanna N Masud, Megha Chandrashekhar, Michael Aregger, …, Anne-Claude Gingras, J Rafael Montenegro-Burke, Jason Moffat
- Nat Chem Biol, 10.1038/s41589-022-01146-9
Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation
- Nicole M Revie, Kali R Iyer, Michelle E Maxson, …, Luke Whitesell, Nicole Robbins, Leah E Cowen
- Nat Commun, 10.1038/s41467-022-31308-1
Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG
- Matthew D Berg, Yanrui Zhu, Raphaël Loll-Krippleber, …, Judit Villén, Grant W Brown, Christopher J Brandl
- G3 (Bethesda), 10.1093/g3journal/jkac125
Correction to: Retention of duplicated genes in evolution: (Trends in Genetics, January 2022, Vol. 38, No. 1)
- Elena Kuzmin, John S Taylor, Charles Boone
- Trends Genet, 10.1016/j.tig.2022.03.014
High-throughput platform for yeast morphological profiling predicts the targets of bioactive compounds
- Shinsuke Ohnuki, Itsuki Ogawa, Kaori Itto-Nakama, …, Grant W Brown, John Ralph, Yoshikazu Ohya
- NPJ Syst Biol Appl, 10.1038/s41540-022-00212-1
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis
- Emmanuel T Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L Gupta
- J Cell Biol, 10.1083/jcb.202010155
Clionamines stimulate autophagy, inhibit Mycobacterium tuberculosis survival in macrophages, and target Pik1
- Rosanne Persaud, Sheena C Li, Joseph D Chao, …, Yossef Av-Gay, Michel Roberge, Raymond J Andersen
- Cell Chem Biol, 10.1016/j.chembiol.2021.07.017
A method for benchmarking genetic screens reveals a predominant mitochondrial bias
- Mahfuzur Rahman, Maximilian Billmann, Michael Costanzo, …, Charles Boone, Jason Moffat, Chad L Myers
- Mol Syst Biol, 10.15252/msb.202010013
Genome-wide screening of genes associated with momilactone B sensitivity in the fission yeast Schizosaccharomyces pombe
- Keisuke Tomita, Yoko Yashiroda, Yasuhiro Matsuo, …, Minoru Yoshida, Hideaki Nojiri, Kazunori Okada
- G3 (Bethesda), 10.1093/g3journal/jkab156
Reduced gene dosage of histone H4 prevents CENP-A mislocalization and chromosomal instability in Saccharomyces cerevisiae
- Jessica R Eisenstatt, Kentaro Ohkuni, Wei-Chun Au, …, Michael Costanzo, Charles Boone, Munira A Basrai
- Genetics, 10.1093/genetics/iyab033
Genetic profiling of protein burden and nuclear export overload
- Reiko Kintaka, Koji Makanae, Shotaro Namba, …, Brenda J Andrews, Charles Boone, Hisao Moriya
- Elife, 10.7554/elife.54080
TheCellVision.org: A Database for Visualizing and Mining High-Content Cell Imaging Projects
- Myra Paz David Masinas, Mojca Mattiazzi Usaj, Matej Usaj, Charles Boone, Brenda J Andrews
- G3 (Bethesda), 10.1534/g3.120.401570
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
- Michael Aregger, Keith A Lawson, Maximillian Billmann, …, Brenda J Andrews, Charles Boone, Jason Moffat
- Nat Metab, 10.1038/s42255-020-0211-z
Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture
- Matthew C Fisher, Sarah J Gurr, Christina A Cuomo, …, Joseph Heitman, Arturo Casadevall, Leah E Cowen
- mBio, 10.1128/mbio.00449-20
Dbf4-Dependent Kinase (DDK)-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A in Saccharomyces cerevisiae
- Jessica R Eisenstatt, Lars Boeckmann, Wei-Chun Au, …, David J Clark, Richard Baker, Munira A Basrai
- G3 (Bethesda), 10.1534/g3.120.401131
Publisher Correction: Integrating yeast chemical genomics and mammalian cell pathway analysis
- Fu-Lai Zhou, Sheena C Li, Yue Zhu, …, Chad L Myers, Charles Boone, Ming-Wei Wang
- Acta Pharmacol Sin, 10.1038/s41401-019-0355-0
Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast
- Wei-Chun Au, Tianyi Zhang, Prashant K Mishra, …, Charles Boone, Peter Kaiser, Munira A Basrai
- PLoS Genet, 10.1371/journal.pgen.1008597
Discovering genetic interactions bridging pathways in genome-wide association studies
- Gang Fang, Wen Wang, Vanja Paunic, …, Charles Boone, Vipin Kumar, Chad L Myers
- Nat Commun, 10.1038/s41467-019-12131-7
Decyl Gallate as a Possible Inhibitor of N-Glycosylation Process in Paracoccidioides lutzii
- Ana Carolina Alves de Paula E Silva, Haroldo Cesar de Oliveira, Liliana Scorzoni, …, Sheena Claire Li, Charles Boone, Maria J S Mendes-Giannini
- Antimicrob Agents Chemother, 10.1128/aac.01909-18
Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase
- Isaac Corcoles-Saez, Jean-Luc Ferat, Michael Costanzo, Charles M Boone, Rita S Cha
- None, 10.15698/mic2019.06.680
Genetic interaction networks in cancer cells
- Barbara Mair, Jason Moffat, Charles Boone, Brenda J Andrews
- Curr Opin Genet Dev, 10.1016/j.gde.2019.03.002
Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases
- Natasha Pascoe, Ashwin Seetharaman, Joan Teyra, …, Charles Boone, Frank Sicheri, Sachdev S Sidhu
- J Mol Biol, 10.1016/j.jmb.2019.02.007
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments
- Scott W Simpkins, Raamesh Deshpande, Justin Nelson, …, Minoru Yoshida, Charles Boone, Chad L Myers
- Nat Protoc, 10.1038/s41596-018-0099-1
Identifying Pseudomonas syringae Type III Secreted Effector Function via a Yeast Genomic Screen
- Amy Huei-Yi Lee, D Patrick Bastedo, Ji-Young Youn, …, Charles M Boone, Darrell Desveaux, David S Guttman
- G3 (Bethesda), 10.1534/g3.118.200877
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions
- Scott W Simpkins, Justin Nelson, Raamesh Deshpande, …, Minoru Yoshida, Charles Boone, Chad L Myers
- PLoS Comput Biol, 10.1371/journal.pcbi.1006532
Essential Function of Mec1, the Budding Yeast ATM/ATR Checkpoint-Response Kinase, in Protein Homeostasis
- Isaac Corcoles-Saez, Kangzhen Dong, Anthony L Johnson, …, Michael Costanzo, Charles Boone, Rita S Cha
- Dev Cell, 10.1016/j.devcel.2018.07.011
A Genome-Wide Screen Reveals a Role for the HIR Histone Chaperone Complex in Preventing Mislocalization of Budding Yeast CENP-A
- Sultan Ciftci-Yilmaz, Wei-Chun Au, Prashant K Mishra, …, Richard E Baker, Charles Boone, Munira A Basrai
- Genetics, 10.1534/genetics.118.301305
Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity
- Can Kayatekin, Audra Amasino, Giorgio Gaglia, …, Charles Boone, Jose C Florez, Susan Lindquist
- Cell, 10.1016/j.cell.2018.02.026