Video highlight
GIL: a python package for designing custom indexing primers
- Nicholas Mateyko, Omar Tariq, Xinyi E Chen, …, Hadis Kamali Deghan, Cassandra Jensen, Carl de Boer
- Bioinformatics, 10.1093/bioinformatics/btad328
Prioritization of autoimmune disease-associated genetic variants that perturb regulatory element activity in T cells
- Kousuke Mouri, Michael H Guo, Carl G de Boer, …, Nir Hacohen, Ryan Tewhey, John P Ray
- Nat Genet, 10.1038/s41588-022-01056-5
The evolution, evolvability and engineering of gene regulatory DNA
- Eeshit Dhaval Vaishnav, Carl G de Boer, Jennifer Molinet, …, Joshua Z Levin, Francisco A Cubillos, Aviv Regev
- Nature, 10.1038/s41586-022-04506-6
Systematic identification of genomic elements that regulate FCGR2A expression and harbor variants linked with autoimmune disease
- Johanna Dahlqvist, Charles P Fulco, John P Ray, …, Jesse M Engreitz, Mario Roederer, Nir Hacohen
- Hum Mol Genet, 10.1093/hmg/ddab372
Global discovery of lupus genetic risk variant allelic enhancer activity
- Xiaoming Lu, Xiaoting Chen, Carmy Forney, …, John B Harley, Matthew T Weirauch, Leah C Kottyan
- Nat Commun, 10.1038/s41467-021-21854-5
MAUDE: inferring expression changes in sorting-based CRISPR screens
- Carl G de Boer, John P Ray, Nir Hacohen, Aviv Regev
- Genome Biol, 10.1186/s13059-020-02046-8
Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features
- John P Ray, Carl G de Boer, Charles P Fulco, …, Eric S Lander, Aviv Regev, Nir Hacohen
- Nat Commun, 10.1038/s41467-020-15022-4
Deciphering eukaryotic gene-regulatory logic with 100 million random promoters
- Carl G de Boer, Eeshit Dhaval Vaishnav, Ronen Sadeh, Esteban Luis Abeyta, Nir Friedman, Aviv Regev
- Nat Biotechnol, 10.1038/s41587-019-0315-8
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
- Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, …, Ryan J Sullivan, Gad Getz, Nir Hacohen
- Cell, 10.1016/j.cell.2018.12.034
Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
- Mati Mann, Arnav Mehta, Carl G de Boer, …, Daneyal Farouq, Aviv Regev, David Baltimore
- Cell Rep, 10.1016/j.celrep.2018.11.056
BROCKMAN: deciphering variance in epigenomic regulators by k-mer factorization
- Carl G de Boer, Aviv Regev
- BMC Bioinformatics, 10.1186/s12859-018-2255-6