Scholar: Brenna Osborne

Brenna Osborne

Nuclear morphology is a deep learning biomarker of cellular senescence

  • Indra Heckenbach, Garik V Mkrtchyan, Michael Ben Ezra, …, Eric Verdin, Rudi Westendorp, Morten Scheibye-Knudsen
  • Nat Aging, 10.1038/s43587-022-00263-3
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ARDD 2020: from aging mechanisms to interventions

  • Garik V Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, …, Daniela Bakula, Alex Zhavoronkov, Morten Scheibye-Knudsen
  • Aging (Albany NY), 10.18632/aging.202454
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A Novel Purification Procedure for Active Recombinant Human DPP4 and the Inability of DPP4 to Bind SARS-CoV-2

  • Cecy R Xi, Arianna Di Fazio, Naveed Ahmed Nadvi, …, Joel P Mackay, W Bret Church, Mark D Gorrell
  • Molecules, 10.3390/molecules25225392
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Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

  • Menghan Liu, Sarah E Hancock, Ghazal Sultani, …, Brenna Osborne, Lake-Ee Quek, Nigel Turner
  • None, 10.3390/jcm8060822
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Impairment of an Endothelial NAD + -H 2 S Signaling Network Is a Reversible Cause of Vascular Aging

  • Abhirup Das, George X Huang, Michael S Bonkowski, …, Zolt Arany, Leonard Guarente, David A Sinclair
  • Cell, 10.1016/j.cell.2019.01.026
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A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

  • Klaartje Somers, Victoria W Wen, Shiloh M C Middlemiss, …, Michelle Haber, Murray D Norris, Michelle J Henderson
  • Oncogene, 10.1038/s41388-018-0666-5
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Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in Cancer

  • Guido Keijzers, Daniela Bakula, Michael Angelo Petr, …, Garik Mkrtchyan, Brenna Osborne, Morten Scheibye-Knudsen
  • Int J Mol Sci, 10.3390/ijms20010074
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A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

  • Nigel Turner, Xin Ying Lim, Hamish D Toop, …, Magdalene K Montgomery, Jonathan C Morris, Anthony S Don
  • Nat Commun, 10.1038/s41467-018-05613-7
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