Defining and using immune archetypes to classify and treat cancer
- Bushra Samad, Bushra Samad, Alexis J Combes, …, Alexis J Combes, Bushra Samad, Matthew F Krummel
- Nat Rev Cancer, 10.1038/s41568-023-00578-2
Transcriptional space-time mapping identifies concerted immune and stromal cell patterns and gene programs in wound healing and cancer
- Kenneth H Hu, Nicholas F Kuhn, Tristan Courau, …, Johannes R Kratz, Alexis J Combes, Matthew F Krummel
- Cell Stem Cell, 10.1016/j.stem.2023.05.001
High-dimensional immune cell profiling of cerebrospinal fluid from patients with metastatic breast cancer and leptomeningeal disease
- L A Huppert, L Malevanchik, H S Rugo, …, M J Campbell, M F Krummel, M E Melisko
- None, 10.1038/s41523-023-00526-1
Dynamic CD8 + TÂ cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes
- Maha K Rahim, Trine Line H Okholm, Kyle B Jones, …, Alain P Algazi, Patrick Ha, Matthew H Spitzer
- Cell, 10.1016/j.cell.2023.02.021
SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants
- Lisiena Hysenaj, Samantha Little, Kayla Kulhanek, …, Melanie Ott, Johannes R Kratz, Jeroen P Roose
- Stem Cell Reports, 10.1016/j.stemcr.2023.01.011
Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells
- Juraj Adamik, Paul V Munson, Felix J Hartmann, …, Sean C Bendall, Rafael J Argüello, Lisa H Butterfield
- Nat Commun, 10.1038/s41467-022-32849-1
Spatiotemporal co-dependency between macrophages and exhausted CD8 + TÂ cells in cancer
- Kelly Kersten, Kenneth H Hu, Alexis J Combes, …, Julia Belk, Ansuman T Satpathy, Matthew F Krummel
- Cancer Cell, 10.1016/j.ccell.2022.05.004
Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
- Marie Laviron, Maxime Petit, Eléonore Weber-Delacroix, …, Christophe Combadière, Matthew F Krummel, Alexandre Boissonnas
- Cell Rep, 10.1016/j.celrep.2022.110865
Deep immunophenotyping reveals endometriosis is marked by dysregulation of the mononuclear phagocytic system in endometrium and peripheral blood
- Júlia Vallvé-Juanico, Ashley F George, Sushmita Sen, …, Nadia R Roan, Alexis J Combes, Linda C Giudice
- BMC Med, 10.1186/s12916-022-02359-4
Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer
- Adriana M Mujal, Alexis J Combes, Arjun A Rao, …, Kevin C Barry, Vincent Chan, Matthew F Krummel
- Cancer Immunol Res, 10.1158/2326-6066.cir-21-0588