Academic lineage
Genome-wide screen identifies host loci that modulate M. tuberculosis fitness in immunodivergent mice
- Rachel K Meade, Jarukit E Long, Adrian Jinich, …, Robert W Williams, Christopher M Sassetti, Clare M Smith
- None, 10.1101/2023.03.05.528534
Enzyme Substrate Prediction from Three-Dimensional Feature Representations Using Space-Filling Curves
- Dmitrij Rappoport, Adrian Jinich, Dmitrij Rappoport, …, Adrian Jinich, Dmitrij Rappoport, Adrian Jinich
- J Chem Inf Model, 10.1021/acs.jcim.3c00005
Deciphering functional redundancy and energetics of malate oxidation in mycobacteria
- Liam K Harold, Adrian Jinich, Kiel Hards, …, Matthew B McNeil, Kyu Rhee, Gregory M Cook
- J Biol Chem, 10.1016/j.jbc.2022.101859
Multiple acyl-CoA dehydrogenase deficiency kills Mycobacterium tuberculosis in vitro and during infection
- Tiago Beites, Robert S Jansen, Ruojun Wang, …, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt
- Nat Commun, 10.1038/s41467-021-26941-1
A thermodynamic atlas of carbon redox chemical space
- Adrian Jinich, Benjamin Sanchez-Lengeling, Haniu Ren, …, Jacob N Sanders, Daniel Segrè, Alán Aspuru-Guzik
- Proc Natl Acad Sci U S A, 10.1073/pnas.2005642117
Extreme Antagonism Arising from Gene-Environment Interactions
- Thomas P Wytock, Manjing Zhang, Adrian Jinich, Aretha Fiebig, Sean Crosson, Adilson E Motter
- Biophys J, 10.1016/j.bpj.2020.09.038
Two for the price of one: Attacking the energetic-metabolic hub of mycobacteria to produce new chemotherapeutic agents
- Kiel Hards, Cara Adolph, Liam K Harold, …, Adrian Jinich, Kyu Y Rhee, Gregory M Cook
- Prog Biophys Mol Biol, 10.1016/j.pbiomolbio.2019.11.003
A Mixed Quantum Chemistry/Machine Learning Approach for the Fast and Accurate Prediction of Biochemical Redox Potentials and Its Large-Scale Application to 315 000 Redox Reactions
- Adrian Jinich, Benjamin Sanchez-Lengeling, Haniu Ren, Rebecca Harman, Alán Aspuru-Guzik
- None, 10.1021/acscentsci.9b00297
Empowering young innovators
- Thomas Sanchez Lengeling, Adrian Jinich
- Science, 10.1126/science.aaw0564
Quantum chemistry reveals thermodynamic principles of redox biochemistry
- Adrian Jinich, Avi Flamholz, Haniu Ren, …, Elad Noor, Alán Aspuru-Guzik, Arren Bar-Even
- PLoS Comput Biol, 10.1371/journal.pcbi.1006471
MultiDK: A Multiple Descriptor Multiple Kernel Approach for Molecular Discovery and Its Application to Organic Flow Battery Electrolytes
- Sungjin Kim, Adrián Jinich, Alán Aspuru-Guzik
- J Chem Inf Model, 10.1021/acs.jcim.6b00332
Quantum chemical approach to estimating the thermodynamics of metabolic reactions
- Adrian Jinich, Dmitrij Rappoport, Ian Dunn, …, Elad Noor, Arren Bar Even, Alán Aspuru-Guzik
- Sci Rep, 10.1038/srep07022