The endoplasmic reticulum (ER) is, in essence, the transportation system of the eukaryotic cell, and has many other important functions such as protein folding. It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER). The endoplasmic reticulum is found in most eukaryotic cells and forms an interconnected network of flattened, membrane-enclosed sacs known as cisternae (in the RER), and tubular structures in the SER. The membranes of the ER are continuous with the outer nuclear membrane. Wikipedia (CC BY-SA 3.0)
2023 Articles
4 424 articles
A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon
- Nir Cohen, Naama Aviram, Maya Schuldiner, …, Nir Cohen, Naama Aviram, Maya Schuldiner
- EMBO J, 10.15252/embj.2022113385
Endoplasmic stress sensor Ire1 is involved in cytosolic/nuclear protein quality control in Pichia pastoris cells independent of HAC1
- Yasmin Nabilah Binti Mohd Fauzee, Yuki Yoshida, Yukio Kimata, …, Yasmin Nabilah Binti Mohd Fauzee, Yuki Yoshida, Yukio Kimata
- None, 10.3389/fmicb.2023.1157146
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane
- Symeon Siniossoglou, Symeon Siniossoglou, Symeon Siniossoglou, Symeon Siniossoglou
- J Cell Biol, 10.1083/jcb.202306126
Lipid biosynthesis perturbation impairs endoplasmic reticulum-associated degradation
- Samantha M Turk, Christopher J Indovina, Jacob M Miller, …, James B Olesen, Philip J Smaldino, Eric M Rubenstein
- J Biol Chem, 10.1016/j.jbc.2023.104939
Autophagy of the ER requires actin assembly driven by the interaction of ER with endocytic pits
- Peter Novick, Dongmei Liu, Susan Ferro-Novick, …, Peter Novick, Dongmei Liu, Susan Ferro-Novick
- None, 10.1177/25152564221093215
Csf1: A Putative Lipid Transport Protein Required for Homeoviscous Adaptation of the Lipidome
- Arun T John Peter, Ngaam J Cheung, Benoît Kornmann, Arun T John Peter, Ngaam J Cheung, Benoît Kornmann
- None, 10.1177/25152564221101974
Overexpression of genes by stress-responsive promoters increases protein secretion in Saccharomyces cerevisiae
- Chufan Xiao, Songlyu Xue, Yuyang Pan, …, Yuyang Pan, Xiufang Liu, Mingtao Huang
- World J Microbiol Biotechnol, 10.1007/s11274-023-03646-9
Ectopic RING activity at the ER membrane differentially impacts ERAD protein quality control pathways
- Adrian B Mehrtash, Mark Hochstrasser, Adrian B Mehrtash, …, Mark Hochstrasser, Adrian B Mehrtash, Mark Hochstrasser
- J Biol Chem, 10.1016/j.jbc.2023.102927
Sec16 and Sed4 interdependently function as interaction and localization partners at ER exit sites
- Tomohiro Yorimitsu, Ken Sato, Tomohiro Yorimitsu, …, Ken Sato, Tomohiro Yorimitsu, Ken Sato
- J Cell Sci, 10.1242/jcs.261094
Increased Phospholipid Flux Bypasses Overlapping Essential Requirements for the Yeast Sac1p Phosphoinositide Phosphatase and ER-PM Membrane Contact Sites
- Aleksa Nenadic, Mohammad F Zaman, Jesper Johansen, …, Jesper Johansen, Matthew W Volpiana, Christopher T Beh
- J Biol Chem, 10.1016/j.jbc.2023.105092
2022 Articles
389 articles
Protein biosynthesis at the ER: finding the right accessories
- Sichen Shao, Sichen Shao, Sichen Shao, Sichen Shao, Sichen Shao, Sichen Shao
- Mol Biol Cell, 10.1091/mbc.e21-09-0451
Co-chaperones of the Human Endoplasmic Reticulum: An Update
- Armin Melnyk, Sven Lang, Mark Sicking, …, Mark Sicking, Richard Zimmermann, Martin Jung
- Subcell Biochem, 10.1007/978-3-031-14740-1_9
An imaging-based RNA interference screen for modulators of the Rab6-mediated Golgi-to-ER pathway in mammalian cells
- Linda F Heffernan, Pia M Suckrau, Teerna Banerjee, …, Teerna Banerjee, Margaritha M Mysior, Jeremy C Simpson
- None, 10.3389/fcell.2022.1050190
Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases
- Inés G de Oya, Elena Jiménez-Gutiérrez, Hélène Gaillard, …, MarÃa Molina, Humberto MartÃn, Ralf Erik Wellinger
- Int J Mol Sci, 10.3390/ijms232415706
Live Cell Imaging of Yeast Golgi Dynamics
- Giancarlo Costaguta, Gregory S Payne, Lydia Daboussi, …, Giancarlo Costaguta, Gregory S Payne, Lydia Daboussi
- Methods Mol Biol, 10.1007/978-1-0716-2639-9_1
The structure of COPI vesicles and regulation of vesicle turnover
- Rebecca J Taylor, Grigory Tagiltsev, John A G Briggs, …, Rebecca J Taylor, Grigory Tagiltsev, John A G Briggs
- FEBS Lett, 10.1002/1873-3468.14560
Yeast Models and Molecular Mechanisms of Neurodegenerative Diseases 2.0
- Joanna Kaminska, Teresa Zoladek, Joanna Kaminska, Teresa Zoladek, Joanna Kaminska, Teresa Zoladek
- Int J Mol Sci, 10.3390/ijms232415821
The 14-3-3γ isoform binds to and regulates the localization of endoplasmic reticulum (ER) membrane protein TMCC3 for the reticular network of the ER
- Saihas Suhda, Yasunori Yamamoto, Sindhu Wisesa, …, Sindhu Wisesa, Risa Sada, Toshiaki Sakisaka
- J Biol Chem, 10.1016/j.jbc.2022.102813
Molecular insights into endolysosomal microcompartment formation and maintenance
- Daniel Kümmel, Eric Herrmann, Lars Langemeyer, …, Eric Herrmann, Lars Langemeyer, Christian Ungermann
- Biol Chem, 10.1515/hsz-2022-0294
Sequence Analysis and Structural Predictions of Lipid Transfer Bridges in the Repeating Beta Groove (RBG) Superfamily Reveal Past and Present Domain Variations Affecting Form, Function and Interactions of VPS13, ATG2, SHIP164, Hobbit and Tweek
- Tim P Levine, Tim P Levine
- None, 10.1177/25152564221134328