Channel: Telomere attrition

Telomere shortening is associated with aging, mortality and aging-related diseases. Normal aging is associated with telomere shortening in both humans and mice. Wikipedia (CC BY-SA 3.0)

2023 Articles

12 946 articles

Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis

  • Venus Marie Gaela, Liuh-Yow Chen, Venus Marie Gaela, …, Liuh-Yow Chen, Venus Marie Gaela, Liuh-Yow Chen
  • Mol Cell, 10.1016/j.molcel.2023.03.012
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Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments

  • Samuel I Bloom, Yu Liu, Jordan R Tucker, …, R Colton Bramwell, Lisa A Lesniewski, Anthony J Donato
  • Aging Cell, 10.1111/acel.13875
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The distribution and accumulation of the shortest telomeres in telomere biology disorders

  • Hannah A Raj, Tsung-Po Lai, Marena R Niewisch, …, Abraham Aviv, Shahinaz M Gadalla, Sharon A Savage
  • Br J Haematol, 10.1111/bjh.18945
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Links between telomere dysfunction and hallmarks of aging

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Proprotein Convertase Subtilisin/Kexin Type 6: A Risk Factor for Survival in Pulmonary Fibrosis?

  • Ivana V Yang, Ivana V Yang, Ivana V Yang, Ivana V Yang, Ivana V Yang, Ivana V Yang
  • Am J Respir Crit Care Med, 10.1164/rccm.202302-0266ed
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Non-canonical telomere protection role of FOXO3a of human skeletal muscle cells regulated by the TRF2-redox axis

  • Maria Sol Jacome Burbano, Jérôme D Robin, Serge Bauwens, …, Sabrina Sacconi, Frédérique Magdinier, Eric Gilson
  • Commun Biol, 10.1038/s42003-023-04903-1
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Gut-specific telomerase expression counteracts systemic aging in telomerase-deficient zebrafish

  • Mounir El Maï, Malia Bird, Asma Allouche, …, Thierry Pourcher, Jia-Xing Yue, Miguel Godinho Ferreira
  • Nat Aging, 10.1038/s43587-023-00401-5
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Generation of Human Induced Pluripotent Stem Cell line from PBMCs of Healthy Donors using Integration-free Sendai virus Technology

  • Swati Chitrangi, Pooja Vaity, Aishwarya Jamdar, …, Aishwarya Jamdar, Hirenkumar Patel, Shweta Bhatt
  • Stem Cell Res, 10.1016/j.scr.2023.103062
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Mammalian aging driven by transcription going awry

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2022 Articles

1 399 articles

Single short reprogramming early in life increases healthspan

  • Jean-Marc Lemaitre, Ollivier Milhavet, Ollivier Milhavet, …, Jean-Marc Lemaitre, Ollivier Milhavet, Jean-Marc Lemaitre
  • Aging (Albany NY), 10.18632/aging.204457
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Regulation of telomere silencing by the core histones-autophagy-Sir2 axis

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Long telomeres at baseline and male sex are main determinants of telomere loss following chemotherapy exposure in lymphoma patients

  • Enrico Derenzini, Angela Gueli, Alessandra Risso, …, Stefano Pileri, Enrico V Avvedimento, Corrado Tarella
  • Hematol Oncol, 10.1002/hon.3118
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Potential Antiaging and Hepatoprotective Effects of Acanthopanax senticosus Extracts in Adult Rat Models

  • Chaeyeong Kim, Hye-Min Bae, Inkyung Baik, …, Chaeyeong Kim, Hye Min Bae, Inkyung Baik
  • Rejuvenation Res, 10.1089/rej.2022.0051
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TERRA increases at short telomeres in yeast survivors and regulates survivor associated senescence (SAS)

  • Stefano Misino, Anke Busch, Carolin B Wagner, …, Carolin B Wagner, Fabio Bento, Brian Luke
  • Nucleic Acids Res, 10.1093/nar/gkac1125
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Identification of Apolipoprotein D as a Dermal Fibroblast Marker of Human Aging for Development of Skin Rejuvenation Therapy

  • Kento Takaya, Toru Asou, Kazuo Kishi, …, Kento Takaya, Toru Asou, Kazuo Kishi
  • Rejuvenation Res, 10.1089/rej.2022.0056
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Genetic basis of enhanced stress resistance in long-lived mutants highlights key role of innate immunity in determining longevity

  • Sonja K Soo, Annika Traa, Zenith D Rudich, …, Alibek Moldakozhayev, Meeta Mistry, Jeremy M Van Raamsdonk
  • Aging Cell, 10.1111/acel.13740
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Paternal aging impacts mitochondrial DNA content and telomere length in mouse embryos

  • Jun Ito, Mio Kageyama, Shunsuke Hara, …, Takuya Sato, Koumei Shirasuna, Hisataka Iwata
  • Mitochondrion, 10.1016/j.mito.2022.12.002
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Impacts of Telomeric Length, Chronic Hypoxia, Senescence, and Senescence-Associated Secretory Phenotype on the Development of Thoracic Aortic Aneurysm

  • Thomas Aschacher, Daniela Geisler, Verena Lenz, …, Marek P Ehrlich, Martin Grabenwöger, Michael Bergmann
  • Int J Mol Sci, 10.3390/ijms232415498
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Role of angiotensin II in aging

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