Inspired by: Peter S Swain
The stochastic nature of gene expression. Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype. Wikipedia (CC BY-SA 3.0)
2023 Articles
1 076 articles
BurstDECONV: a signal deconvolution method to uncover mechanisms of transcriptional bursting in live cells
- Maria Douaihy, Rachel Topno, Mounia Lagha, Edouard Bertrand, Ovidiu Radulescu
- Nucleic Acids Res, 10.1093/nar/gkad629
Inferring transcriptional bursting kinetics from single-cell snapshot data using a generalized telegraph model
- Songhao Luo, Zhenquan Zhang, Zihao Wang, …, Xiaoxuan Chen, Tianshou Zhou, Jiajun Zhang
- None, 10.1098/rsos.221057
Unified bursting strategies in ectopic and endogenous even-skipped expression patterns
- Augusto Berrocal, Nicholas C Lammers, Hernan G Garcia, …, Nicholas C Lammers, Hernan G Garcia, Michael B Eisen
- bioRxiv : the preprint server for biology, 10.1101/2023.02.09.527927
The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian
- Douglas E Weidemann, Abhyudai Singh, Ramon Grima, …, Abhyudai Singh, Ramon Grima, Silke Hauf
- bioRxiv : the preprint server for biology, 10.1101/2023.03.06.531283
Dynamic epistasis analysis reveals how chromatin remodeling regulates transcriptional bursting
- Ineke Brouwer, Emma Kerklingh, Fred van Leeuwen, …, Emma Kerklingh, Fred van Leeuwen, Tineke L Lenstra
- Nat Struct Mol Biol, 10.1038/s41594-023-00981-1
The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian
- Douglas E Weidemann, James Holehouse, Abhyudai Singh, …, Abhyudai Singh, Ramon Grima, Silke Hauf
- Sci Adv, 10.1126/sciadv.adh5138
Transcriptional bursting: stochasticity in deterministic development
- Emilia A Leyes Porello, Robert T Trudeau, Bomyi Lim, …, Emilia A Leyes Porello, Robert T Trudeau, Bomyi Lim
- Development, 10.1242/dev.201546
Stochastic scanning events on the GCN4 mRNA 5′ untranslated region generate cell-to-cell heterogeneity in the yeast nutritional stress response
- Xiang Meng, Alan Reed, Sandie Lai, …, Sandie Lai, Juraj Szavits-Nossan, John E G McCarthy
- Nucleic Acids Res, 10.1093/nar/gkad433
Development of Terminator-Promoter Bifunctional Elements for Application in Saccharomyces cerevisiae Pathway Engineering
- Xiaoxia Ni, Zhengyang Liu, Jintang Guo, …, Zhengyang Liu, Jintang Guo, Genlin Zhang
- Int J Mol Sci, 10.3390/ijms24129870
Transcription activator WCC recruits deacetylase HDA3 to control transcription dynamics and bursting in Neurospora
- Michael Oehler, Leonie Geisser, Axel C R Diernfellner, …, Leonie Geisser, Axel C R Diernfellner, Michael Brunner
- Sci Adv, 10.1126/sciadv.adh0721
2022 Articles
98 articles
Enhanced Transcriptional Strength of HIV-1 Subtype C Minimizes Gene Expression Noise and Confers Stability to the Viral Latent State
- Sreshtha Pal, Vijeta Jaiswal, Narendra Nala, …, Vijeta Jaiswal, Narendra Nala, Udaykumar Ranga
- J Virol, 10.1128/jvi.01376-22
Genome-wide inference reveals that feedback regulations constrain promoter-dependent transcriptional burst kinetics
- Songhao Luo, Zihao Wang, Zhenquan Zhang, …, Zhenquan Zhang, Tianshou Zhou, Jiajun Zhang
- Nucleic Acids Res, 10.1093/nar/gkac1204
Transcription factor binding process is the primary driver of noise in gene expression
- Lavisha Parab, Sampriti Pal, Riddhiman Dhar, …, Lavisha Parab, Sampriti Pal, Riddhiman Dhar
- PLoS Genet, 10.1371/journal.pgen.1010535
STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity
- Hiroaki Ohishi, Seiru Shimada, Satoshi Uchino, …, Takashi Yamamoto, Hiroshi Kimura, Hiroshi Ochiai
- Nat Commun, 10.1038/s41467-022-35286-2
Impact of Saccharomyces cerevisiae on the Field of Single-Molecule Biophysics
- David A Ball, Binta Jalloh, Tatiana S Karpova, …, David A Ball, Binta Jalloh, Tatiana S Karpova
- Int J Mol Sci, 10.3390/ijms232415895
Predictive modeling reveals that higher-order cooperativity drives transcriptional repression in a synthetic developmental enhancer
- Yang Joon Kim, Kaitlin Rhee, Jonathan Liu, …, Meghan A Turner, Stephen J Small, Hernan G Garcia
- Elife, 10.7554/elife.73395
Polarization and cell-fate decision facilitated by the adaptor Ste50p in Saccharomyces cerevisiae
- Nusrat Sharmeen, Chris Law, Cunle Wu, …, Nusrat Sharmeen, Chris Law, Cunle Wu
- PLoS One, 10.1371/journal.pone.0278614
Variable DNA topology is an epigenetic generator of physiological heterogeneity in bacterial populations
- Charles J Dorman, Charles J Dorman, Charles J Dorman, …, Charles J Dorman, Charles J Dorman, Charles J Dorman
- Mol Microbiol, 10.1111/mmi.15014
Chromatin modules and their implication in genomic organization and gene regulation
- Guido van Mierlo, Olga Pushkarev, Judith F Kribelbauer, …, Olga Pushkarev, Judith F Kribelbauer, Bart Deplancke
- Trends Genet, 10.1016/j.tig.2022.11.003
Novel biological insights revealed from the investigation of multiscale genome architecture
- Tianyi Ding, He Zhang, Tianyi Ding, He Zhang
- None, 10.1016/j.csbj.2022.12.009