Channel: Stem cell exhaustion

Loss of regenerative ability is one of the most obvious consequences of aging. This is largely because the proportion of stem cells and the speed of their division gradually lowers over time. Wikipedia (CC BY-SA 3.0)

2023 Articles

48 438 articles

Mitochondria: A “pacemaker” for species-specific development

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Dipping a toe in the fountain of youth

  • Arianna Markel, Arianna Markel, Arianna Markel, George Q Daley, Arianna Markel, George Q Daley
  • Nat Aging, 10.1038/s43587-022-00188-x
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Hematopoietic heterogeneity starts at the hemogenic endothelium

  • Eline Lemerle, Eirini Trompouki, Eline Lemerle, …, Eirini Trompouki, Eline Lemerle, Eirini Trompouki
  • Cell Res, 10.1038/s41422-023-00806-2
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PU.1 is required to restrain myelopoiesis during chronic inflammatory stress

  • James S Chavez, Jennifer L Rabe, Katia E Niño, …, Taylor S Mills, Giovanny Hernandez, Eric M Pietras
  • None, 10.3389/fcell.2023.1204160
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Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs

  • Xiaoqing Xie, Pradeep Kumar Patnana, Daria Frank, …, Nikolas Von Bubnoff, Georg Lenz, Cyrus Khandanpour
  • None, 10.3389/fcell.2023.866847
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Hematopoiesis: a BETter understanding

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Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with small molecules

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KDM6A/B Demethylases in Gut Homeostasis

  • Natalia Soshnikova, Natalia Soshnikova, Natalia Soshnikova, …, Natalia Soshnikova, Natalia Soshnikova, Natalia Soshnikova
  • Cell Mol Gastroenterol Hepatol, 10.1016/j.jcmgh.2022.12.017
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Long noncoding RNA CR46040 is essential for injury-stimulated regeneration of intestinal stem cells in Drosophila

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2022 Articles

5 270 articles

Single short reprogramming early in life increases healthspan

  • Jean-Marc Lemaitre, Ollivier Milhavet, Ollivier Milhavet, …, Jean-Marc Lemaitre, Ollivier Milhavet, Jean-Marc Lemaitre
  • Aging (Albany NY), 10.18632/aging.204457
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Heterogeneous levels of delta-like 4 within a multinucleated niche cell maintains muscle stem cell diversity

  • Susan Eliazer, Xuefeng Sun, Emilie Barruet, …, Xuefeng Sun, Emilie Barruet, Andrew S Brack
  • Elife, 10.7554/elife.68180
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Studying human neural function in vivo at the cellular level: Chasing chimeras?

  • Ben Vermaercke, Vincent Bonin, Pierre Vanderhaeghen, …, Ben Vermaercke, Vincent Bonin, Pierre Vanderhaeghen
  • Cell, 10.1016/j.cell.2022.11.020
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The adult Drosophila testis lacks a mechanism to replenish missing niche cells

  • Phylis Hétié, Margaret de Cuevas, Erika L Matunis, …, Phylis Hétié, Margaret de Cuevas, Erika L Matunis
  • Development, 10.1242/dev.201148
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When and how did the first blood cells evolve?

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Atypical cell cycle profile of mouse embryonic stem cell is regulated by classic oncogenic and tumor suppressive genes in vitro

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The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons

  • Catherine Schaefers, Simone Rothmiller, Horst Thiermann, …, Horst Thiermann, Theo Rein, Annette Schmidt
  • None, 10.1155/2022/1320950
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Sox17 mediates adult arterial endothelial cell adaptation to hemodynamics

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Glycolytic Regulation of Intestinal Stem Cell Self-Renewal and Differentiation

  • Chang Li, Yuning Zhou, Ruozheng Wei, …, Heidi L Weiss, Qingding Wang, B Mark Evers
  • Cell Mol Gastroenterol Hepatol, 10.1016/j.jcmgh.2022.12.012
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Expression dynamics of lymphoid enhancer-binding factor 1 in terminal Schwann cells, dermal papilla, and interfollicular epidermis

  • Hongzhi Song, Xu-Bo Zhao, Qing-Song Chu, …, Jianyu Zhang, Lipeng Gao, Xin-Hua Liao
  • Dev Dyn, 10.1002/dvdy.562
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