Inspired by: D Allan Drummond
A prion /ˈpriːɒn/ ⓘ is a misfolded protein that can transmit its misfoldedness to normal variants of the same protein and trigger cellular death. Prions cause prion diseases known as transmissible spongiform encephalopathies (TSEs) that are transmissible, fatal neurodegenerative diseases in humans and animals. The proteins may misfold sporadically, due to genetic mutations, or by exposure to an already misfolded protein. The consequent abnormal three-dimensional structure confers on them the ability to cause misfolding of other proteins. Wikipedia (CC BY-SA 3.0)
2023 Articles
532 articles
Functional characterization and comparative analysis of gene repression-mediating domains interacting with yeast pleiotropic corepressors Sin3, Cyc8 and Tup1
- Julia Lettow, Felix Kliewe, Rasha Aref, …, Felix Kliewe, Rasha Aref, Hans-Joachim Schüller
- Curr Genet, 10.1007/s00294-023-01262-6
Differing SAGA module requirements for NCR-sensitive gene transcription in yeast
- Isabelle Georis, Aria Ronsmans, Fabienne Vierendeels, Evelyne Dubois
- Yeast, 10.1002/yea.3885
Genetic inactivation of essential HSF1 reveals an isolated transcriptional stress response selectively induced by protein misfolding
- Michela Ciccarelli, Anna E Masser, Jayasankar Mohanakrishnan Kaimal, …, Jayasankar Mohanakrishnan Kaimal, Jordi Planells, Claes Andréasson
- Mol Biol Cell, 10.1091/mbc.e23-05-0153
How Big Is the Yeast Prion Universe?
- Galina A Zhouravleva, Stanislav A Bondarev, Nina P Trubitsina, …, Galina A Zhouravleva, Stanislav A Bondarev, Nina P Trubitsina
- Int J Mol Sci, 10.3390/ijms241411651
TorC1 and nitrogen catabolite repression control of integrated GABA shunt and retrograde pathway gene expression
- Jennifer J Tate, Rajendra Rai, Terrance G Cooper, …, Jennifer J Tate, Rajendra Rai, Terrance G Cooper
- Yeast, 10.1002/yea.3849
Transcription by the Three RNA Polymerases under the Control of the TOR Signaling Pathway in Saccharomyces cerevisiae
- Francisco Gutiérrez-Santiago, Francisco Navarro, Francisco Gutiérrez-Santiago, …, Francisco Navarro, Francisco Gutiérrez-Santiago, Francisco Navarro
- Biomolecules, 10.3390/biom13040642
Balanced activities of Hsp70 and the ubiquitin proteasome system underlie cellular protein homeostasis
- Areeb Jawed, Chi-Ting Ho, Tomas Grousl, …, Thomas Ruppert, Bernd Bukau, Axel Mogk
- None, 10.3389/fmolb.2022.1106477
A Gene from Ganoderma lucidum with Similarity to nmrA of Filamentous Ascomycetes Contributes to Regulating AreA
- He Liu, Jinjin Qiao, Jiaolei Shangguan, …, Xiaolin Zhou, Mingwen Zhao, Jing Zhu
- None, 10.3390/jof9050516
Domains and residues of the Saccharomyces cerevisiae hnRNP protein Hrp1 important for transcriptional autoregulation and noncoding RNA termination
- Emma C Goguen, David A Brow, Emma C Goguen, …, David A Brow, Emma C Goguen, David A Brow
- Genetics, 10.1093/genetics/iyad134
The Ubiquitin-like Proteins of Saccharomyces cerevisiae
- Swarnab Sengupta, Elah Pick, Swarnab Sengupta, …, Elah Pick, Swarnab Sengupta, Elah Pick
- Biomolecules, 10.3390/biom13050734
2022 Articles
61 articles
Nucleotide Exchange Factors for Hsp70 Molecular Chaperones: GrpE, Hsp110/Grp170, HspBP1/Sil1, and BAG Domain Proteins
- Andreas Bracher, Jacob Verghese, Andreas Bracher, Jacob Verghese, Andreas Bracher, Jacob Verghese
- Subcell Biochem, 10.1007/978-3-031-14740-1_1
PSMC3 promotes RNAi by maintaining AGO2 stability through USP14
- Jianing Zhao, Tao Yu, Xue Zhang, …, Tongxin Hao, Zeyuan Jin, Xiaoqing Zhao
- Cell Mol Biol Lett, 10.1186/s11658-022-00411-y
A pioneer factor locally opens compacted chromatin to enable targeted ATP-dependent nucleosome remodeling
- Megan A Frederick, Kaylyn E Williamson, Meilin Fernandez Garcia, …, Janice Reynaga, Cigall Kadoch, Kenneth S Zaret
- Nat Struct Mol Biol, 10.1038/s41594-022-00886-5
Effect of evolution of the C-terminal region on chaperone activity of Hsp70
- Hong Zhang, Huimin Hu, Si Wu, …, Huimin Hu, Si Wu, Sarah Perrett
- Protein Sci, 10.1002/pro.4549
Expanded in vivo substrate profile of the yeast N-terminal acetyltransferase NatC
- Petra Van Damme, Camilla Osberg, Veronique Jonckheere, …, Kris Gevaert, Thomas Arnesen, Henriette Aksnes
- J Biol Chem, 10.1016/j.jbc.2022.102824
HSP70-HSP90 Chaperone Networking in Protein-Misfolding Disease
- Chrisostomos Prodromou, Xavi Aran-Guiu, Jasmeen Oberoi, …, Laura Perna, J Paul Chapple, Jacqueline van der Spuy
- Subcell Biochem, 10.1007/978-3-031-14740-1_13
A minimal construct of nuclear-import receptor Karyopherin-β2 defines the regions critical for chaperone and disaggregation activity
- Charlotte M Fare, Kevin Rhine, Andrew Lam, …, Andrew Lam, Sua Myong, James Shorter
- J Biol Chem, 10.1016/j.jbc.2022.102806
Hsp70/Hsp90 Organising Protein (Hop): Coordinating Much More than Chaperones
- Kelly Schwarz, Swati Baindur-Hudson, Gregory Lloyd Blatch, …, Swati Baindur-Hudson, Gregory Lloyd Blatch, Adrienne Lesley Edkins
- Subcell Biochem, 10.1007/978-3-031-14740-1_3
Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy
- Anna Niewiadomska-Cimicka, Antoine Hache, Stéphanie Le Gras, …, Emmanuelle Clérin, Thierry Léveillard, Yvon Trottier
- J Biomed Sci, 10.1186/s12929-022-00892-1
Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation
- Bing Sun, McLean Sherrin, Richard Roy, …, Bing Sun, McLean Sherrin, Richard Roy
- Nucleic Acids Res, 10.1093/nar/gkac1155