Polycystic kidney disease (PKD or PCKD, also known as polycystic kidney syndrome) is a genetic disorder in which the renal tubules become structurally abnormal, resulting in the development and growth of multiple cysts within the kidney. Wikipedia (CC BY-SA 3.0)
2023 Articles
363 articles
How organoids are advancing the understanding of chronic kidney disease
- Eric Bender, Eric Bender, Eric Bender, Eric Bender
- Nature, 10.1038/d41586-023-00652-7
Preparation of Human Kidney Progenitor Cultures and Their Differentiation into Podocytes
- Maria Elena Melica, Maria Lucia Angelotti, Giulia Antonelli, …, Elena Lazzeri, Laura Lasagni, Paola Romagnani
- None, 10.21769/bioprotoc.4757
The “3Ds” of Growing Kidney Organoids: Advances in Nephron Development, Disease Modeling, and Drug Screening
- Brooke E Chambers, Nicole E Weaver, Rebecca A Wingert, …, Brooke E Chambers, Nicole E Weaver, Rebecca A Wingert
- Cells, 10.3390/cells12040549
Single-cell RNA sequencing and kidney organoid differentiation
- Kohei Uchimura
- Clin Exp Nephrol, 10.1007/s10157-023-02359-5
Organoids are not organs: Sources of variation and misinformation in organoid biology
- Kim Bak Jensen, Melissa Helen Little, Kim Bak Jensen, …, Melissa Helen Little, Kim Bak Jensen, Melissa Helen Little
- Stem Cell Reports, 10.1016/j.stemcr.2023.05.009
Permissive ureter specification by TBX18-mediated repression of metanephric gene expression
- Anna-Carina Weiss, Eva Blank, Tobias Bohnenpoll, …, Makoto Mark Taketo, Mark-Oliver Trowe, Andreas Kispert
- Development, 10.1242/dev.201048
Polycystic kidneys: interaction of notch and renin
- Emily A Daniel, Nicole A Sommer, Madhulika Sharma, …, Emily A Daniel, Nicole A Sommer, Madhulika Sharma
- Clin Sci (Lond), 10.1042/cs20230023
Disease modeling of ADAMTS9-related nephropathy using kidney organoids reveals its roles in tubular cells and podocytes
- Seyoung Yu, Yo Jun Choi, John Hoon Rim, …, Friedhelm Hildebrandt, Mir Reza Bekheirnia, Heon Yung Gee
- None, 10.3389/fmed.2023.1089159
Single-cell sequencing of individual retinal organoids reveals determinants of cell-fate heterogeneity
- Amy Tresenrider, Akshayalakshmi Sridhar, Kiara C Eldred, …, Dawn Hoffer, Cole Trapnell, Thomas A Reh
- Cell Rep Methods, 10.1016/j.crmeth.2023.100548
Cells sorted off hiPSC-derived kidney organoids coupled with immortalized cells reliably model the proximal tubule
- Ramin Banan Sadeghian, Ryohei Ueno, Yuji Takata, …, Toshikazu Araoka, Minoru Takasato, Ryuji Yokokawa
- Commun Biol, 10.1038/s42003-023-04862-7
2022 Articles
47 articles
Opportunities and Challenges of Human IPSC Technology in Kidney Disease Research
- Jia-Jung Lee, Chuang-Yu Lin, Hung-Chun Chen, …, Patrick C H Hsieh, Yi-Wen Chiu, Jer-Ming Chang
- None, 10.3390/biomedicines10123232
Glucose absorption drives cystogenesis in a human organoid-on-chip model of polycystic kidney disease
- Sienna R Li, Ramila E Gulieva, Louisa Helms, …, Hongxia Fu, Jonathan Himmelfarb, Benjamin S Freedman
- Nat Commun, 10.1038/s41467-022-35537-2
Overexpression of notch signaling in renin cells leads to a polycystic kidney phenotype
- Brian C Belyea, Fang Xu, Margaret Wiltsie, …, Agnes B Fogo, Maria Luisa Soledad Sequeira-Lopez, Roberto Ariel Gomez
- Clin Sci (Lond), 10.1042/cs20220496
Role of extracellular matrix components and structure in new renal models in vitro
- Alodia Lacueva-Aparicio, Rafael Soares Lindoso, Silvia M Mihăilă, …, Rafael Soares Lindoso, Silvia M Mihăilă, Ignacio Giménez
- None, 10.3389/fphys.2022.1048738
Primary Cilia: The New Face of Craniofacial Research
- Emily R Moore, Emily R Moore, Emily R Moore, Emily R Moore
- Biomolecules, 10.3390/biom12121724
Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases
- Beatrice Xuan Ho, Jeremy Kah Sheng Pang, Ying Chen, …, Woon-Khiong Chan, Shi Yan Ng, Boon Seng Soh
- Stem Cell Res Ther, 10.1186/s13287-022-03215-1
Transcription factor HNF1β controls a transcriptional network regulating kidney cell structure and tight junction integrity
- Lotte E Tholen, Femke Latta, Joost H A Martens, …, Joost H A Martens, Joost G J Hoenderop, Jeroen H F de Baaij
- Am J Physiol Renal Physiol, 10.1152/ajprenal.00199.2022
Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination
- Giada Delfino, Karelle Bénardais, Julien Graff, …, Maria Cristina Antal, M Said Ghandour, Nelly Boehm
- None, 10.3389/fncel.2022.1049468
Caspase-1 and the inflammasome promote polycystic kidney disease progression
- Katherine I Swenson-Fields, Christopher J Ward, Micaila E Lopez, …, Darren P Wallace, Michael P Vitek, Timothy A Fields
- None, 10.3389/fmolb.2022.971219
The Centrosome Cycle within the Cell Cycle
- Heide Schatten, Heide Schatten, Heide Schatten
- Adv Anat Embryol Cell Biol, 10.1007/978-3-031-20848-5_2