An oxygenase is any enzyme that oxidizes a substrate by transferring the oxygen from molecular oxygen O2 (as in air) to it. The oxygenases form a class of oxidoreductases; their EC number is EC 1.13 or EC 1.14. Wikipedia (CC BY-SA 3.0)
2023 Articles
263 articles
Synergistic Binding of the Halide and Cationic Prime Substrate of l-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States
- Jeffrey W Slater, Chi-Yun Lin, Monica E Neugebauer, …, Alexey Silakov, Carsten Krebs, J Martin Bollinger
- Biochemistry, 10.1021/acs.biochem.3c00248
Coordination Dynamics of Iron is a Key Player in the Catalysis of Non-heme Enzymes
- Jinyan Zhang, Peng Wu, Xuan Zhang, …, Peng Wu, Xuan Zhang, Binju Wang
- Chembiochem, 10.1002/cbic.202300119
Iron(II)-α-keto acid complexes of tridentate ligands on gold nanoparticles: the effect of ligand geometry and immobilization on their dioxygen-dependent reactivity
- Abhijit Bera, Debobrata Sheet, Tapan Kanti Paine
- Dalton Trans, 10.1039/d2dt02433k
Nuclear Resonance Vibrational Spectroscopy Definition of Peroxy Intermediates in Catechol Dioxygenases: Factors that Determine Extra- versus Intradiol Cleavage
- Jeffrey T Babicz, Melanie S Rogers, Dory E DeWeese, …, Makoto Seto, John D Lipscomb, Edward I Solomon
- J Am Chem Soc, 10.1021/jacs.3c02242
Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions
- Ilia G Denisov, Stephen G Sligar, Ilia G Denisov, …, Stephen G Sligar, Ilia G Denisov, Stephen G Sligar
- J Inorg Biochem, 10.1016/j.jinorgbio.2023.112202
Elusive Active Intermediates and Reaction Mechanisms of ortho-/ipso-Hydroxylation of Benzoic Acid by Hydrogen Peroxide Mediated by Bioinspired Iron(II) Catalysts
- Zhimin Wu, Xuan Zhang, Lanping Gao, …, Yufen Zhao, Wonwoo Nam, Yong Wang
- Inorg Chem, 10.1021/acs.inorgchem.3c01576
A human protein hydroxylase that accepts D-residues
- Hwanho Choi, Adam P Hardy, Thomas M Leissing, …, Michael A McDonough, Hwangseo Park, Christopher J Schofield
- None, 10.1038/s42004-020-0290-5
Reactivity Differences of Trigonal Pyramidal Nonheme Iron(IV)-Oxo and Iron(III)-Oxo Complexes: Experiment and Theory
- Yuanxin Cao, Juan A Valdez-Moreira, Sam Hay, …, Sam Hay, Jeremy M Smith, Sam P de Visser
- Chemistry, 10.1002/chem.202300271
Dynamic Domain Links Substrate Binding and Catalysis in the Factor-Inhibiting-HIF-1
- Cristina B Martin, Cornelius Y Taabazuing, Michael J Knapp, Cristina B Martin, Cornelius Y Taabazuing, Michael J Knapp
- Biochemistry, 10.1021/acs.biochem.3c00231
Repurposing Iron- and 2-Oxoglutarate-Dependent Oxygenases to Catalyze Olefin Hydration
- Bingnan Wang, Yong Lu, Lide Cha, …, Yisong Guo, Wei-Chen Chang, Chuo Chen
- Angew Chem Int Ed Engl, 10.1002/anie.202311099
2022 Articles
15 articles
Mechanistic Insight into Peptidyl-Cysteine Oxidation by the Copper-Dependent Formylglycine-Generating Enzyme
- Yao Wu, Cong Zhao, Yanzhuang Su, …, Yanzhuang Su, Sason Shaik, Wenzhen Lai
- Angew Chem Int Ed Engl, 10.1002/anie.202212053
Contrasting Mechanisms of Aromatic and Aryl-Methyl Substituent Hydroxylation by the Rieske Monooxygenase Salicylate 5-Hydroxylase
- Melanie S Rogers, Adrian M Gordon, Todd M Rappe, …, Todd M Rappe, Jason D Goodpaster, John D Lipscomb
- Biochemistry, 10.1021/acs.biochem.2c00610
A Compound I Mimic Reveals the Transient Active Species of a Cytochrome P450 Enzyme: Insight into the Stereoselectivity of P450-Catalysed Oxidations
- Kazuto Suzuki, Joshua Kyle Stanfield, Keita Omura, …, Yuichiro Aiba, Hiroshi Sugimoto, Osami Shoji
- Angew Chem Int Ed Engl, 10.1002/anie.202215706
Bio-inspired Cu(II) amido-quinoline complexes as catalysts for aromatic C-H bond hydroxylation
- Monika, Aniruddha Sarkar, Naiwrit Karmodak, …, Naiwrit Karmodak, Basab Bijayi Dhar, Sanjay Adhikari
- Dalton Trans, 10.1039/d2dt03242b
H2O2-Driven Hydroxylation of Steroids Catalyzed by Cytochrome P450 CYP105D18: Exploration of the Substrate Access Channel
- Bashu Dev Pardhe, Kyoung Pyo Kwon, Jong Kook Park, …, Jong Kook Park, Jun Hyuck Lee, Tae-Jin Oh
- Appl Environ Microbiol, 10.1128/aem.01585-22
Comparative oxidative ability of mononuclear and dinuclear high-valent iron-oxo species towards the activation of methane: does the axial/bridge atom modulate the reactivity?
- Mursaleem Ansari, Mursaleem Ansari, Mursaleem Ansari, Gopalan Rajaraman
- Dalton Trans, 10.1039/d2dt02559k
Enantioselective Single and Dual α-C-H Bond Functionalization of Cyclic Amines via Enzymatic Carbene Transfer
- Xinkun Ren, Bo M Couture, Ningyu Liu, …, Manjinder S Lall, Jeffrey T Kohrt, Rudi Fasan
- J Am Chem Soc, 10.1021/jacs.2c10775
Insight into Different Stages of Steroid Degradation in Thermophilic Saccharopolyspora hirsuta VKM Ac-666T Strain
- Tatyana Lobastova, Victoria Fokina, Irina Pozdnyakova-Filatova, …, Sergey Tarlachkov, Andrey Shutov, Marina Donova
- Int J Mol Sci, 10.3390/ijms232416174
Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids
- Md Khalilur Rahman, Balasubrahmanyam Umashankar, Hassan Choucair, …, Colin R Dunstan, Tristan Rawling, Michael Murray
- Eur J Pharmacol, 10.1016/j.ejphar.2022.175470
Zn(II)-Catalyzed Selective N-Alkylation of Amines with Alcohols Using Redox Noninnocent Azo-Aromatic Ligand as Electron and Hydrogen Reservoir
- Subhajit Chakraborty, Rakesh Mondal, Subhasree Pal, …, Amit Kumar Guin, Lisa Roy, Nanda D Paul
- J Org Chem, 10.1021/acs.joc.2c01773