Channel: Next-generation sequencing

Next-generation sequencing (NGS), sometimes referred to as high-throughput sequencing, represents a group of modern sequencing technologies that allow for the rapid and simultaneous sequencing of many DNA or RNA molecules. These technologies have revolutionized genomics, transcriptomics, and other fields by significantly reducing the cost per sequenced base and increasing the throughput of sequencing experiments. ChatGPT (CC BY 4.0)

2023 Articles

13 445 articles

Method of the year: long-read sequencing

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LRphase: an efficient method for assigning haplotype identity to long reads

  • Monica J Holmes, Babak Mahjour, Christopher P Castro, …, Gregory A Farnum, Adam G Diehl, Alan P Boyle
  • bioRxiv : the preprint server for biology, 10.1101/2023.01.18.524565
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Human populations are not biologically and genetically discrete

  • Martin S Fischer, Johannes Krause, Martin S Fischer, …, Johannes Krause, Martin S Fischer, Johannes Krause
  • Br J Psychol, 10.1111/bjop.12635
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The human pangenome reference anticipates equitable and fundamental genomic insights

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LRez: a C++ API and toolkit for analyzing and managing Linked-Reads data

  • Pierre Morisse, Claire Lemaitre, Fabrice Legeai, Pierre Morisse, Claire Lemaitre, Fabrice Legeai
  • None, 10.1093/bioadv/vbab022
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HQAlign: Aligning nanopore reads for SV detection using current-level modeling

  • Dhaivat Joshi, Suhas Diggavi, Mark J P Chaisson, …, Suhas Diggavi, Mark J P Chaisson, Sreeram Kannan
  • bioRxiv : the preprint server for biology, 10.1101/2023.01.08.523172
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ATAC-seq Data Processing

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SAMStat 2: quality control for next generation sequencing data

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NanoSTR: A method for detection of target short tandem repeats based on nanopore sequencing data

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Structural Refinement by Direct Mapping Reveals Assembly Inconsistencies near Hi-C Junctions

  • Luca Marcolungo, Leonardo Vincenzi, Matteo Ballottari, …, Matteo Orlandi, Marzia Rossato, Massimo Delledonne
  • None, 10.3390/plants12020320
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2022 Articles

1 272 articles

NanoSNP: a progressive and haplotype-aware SNP caller on low-coverage nanopore sequencing data

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Analysis of mutational genotyping using correctable decoding sequencing with superior specificity

  • Pengfeng Xiao, Huan Huang, Zuhong Lu, …, Huan Huang, Guohua Zhou, Zuhong Lu
  • Analyst, 10.1039/d2an01805e
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Truvari: refined structural variant comparison preserves allelic diversity

  • Vipin K Menon, Richard A Gibbs, Ginger A Metcalf, …, Richard A Gibbs, Ginger A Metcalf, Fritz J Sedlazeck
  • Genome Biol, 10.1186/s13059-022-02840-6
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YaHS: yet another Hi-C scaffolding tool

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CNV-PCC: An efficient method for detecting copy number variations from next-generation sequencing data

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Open-Access Worldwide Population STR Database Constructed Using High-Coverage Massively Parallel Sequencing Data Obtained from the 1000 Genomes Project

  • Tamara Soledad Frontanilla, Guilherme Valle-Silva, Jesus Ayala, …, Guilherme Valle-Silva, Jesus Ayala, Celso Teixeira Mendes-Junior
  • Genes (Basel), 10.3390/genes13122205
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Analysis of Ancient Microbial DNA

  • Olivier Gorgé, E Andrew Bennett, Diyendo Massilani, …, Julien Daligault, Eva-Maria Geigl, Thierry Grange
  • Methods Mol Biol, 10.1007/978-1-0716-2871-3_6
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Simultaneous profiling of histone modifications and DNA methylation via nanopore sequencing

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InDelGT: An integrated pipeline for extracting indel genotypes for genetic mapping in a hybrid population using next-generation sequencing data

  • Zhiliang Pan, Jinpeng Zhang, Shengjun Bai, …, Shengjun Bai, Zhiting Li, Chunfa Tong
  • None, 10.1002/aps3.11499
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Three assays for in-solution enrichment of ancient human DNA at more than a million SNPs

  • Nadin Rohland, Swapan Mallick, Matthew Mah, …, Robert Maier, Nick Patterson, David Reich
  • Genome Res, 10.1101/gr.276728.122
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