New antigens produced by cancer cells that can be recognized by the immune system as foreign. ChatGPT (CC BY 4.0)
2023 Articles
1 777 articles
Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines
- Ana Barajas, Carla Rovirosa, Raquel Ortiz, …, Bonaventura Clotet, Julià Blanco, Jorge Carrillo
- Cancer Immunol Immunother, 10.1007/s00262-023-03409-3
DeepNeo: a webserver for predicting immunogenic neoantigens
- Jeong Yeon Kim, Hyoeun Bang, Seung-Jae Noh, …, Hyoeun Bang, Seung-Jae Noh, Jung Kyoon Choi
- Nucleic Acids Res, 10.1093/nar/gkad275
Identification of patient-specific CD4+ and CD8+ T cell neoantigens through HLA-unbiased genetic screens
- Chiara M Cattaneo, Thomas Battaglia, Jos Urbanus, …, Emile E Voest, Ton N Schumacher, Wouter Scheper
- Nat Biotechnol, 10.1038/s41587-022-01547-0
Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry
- Kshiti Meera Phulphagar, Claudia Ctortecka, Alvaro Sebastian Vaca Jacome, …, Karl Clauser, Jennifer Abelin, Steven A Carr
- bioRxiv : the preprint server for biology, 10.1101/2023.03.10.532106
Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity
- Talar Tokatlian, Grace E Asuelime, Martin S Naradikian, …, Dora Toledo Warshaviak, Alexander Kamb, Agnes E Hamburger
- Cancer Res Commun, 10.1158/2767-9764.crc-21-0165
Unraveling tumor specific neoantigen immunogenicity prediction: a comprehensive analysis
- Guadalupe Nibeyro, Veronica Baronetto, Juan I Folco, …, Gabriel Morón, Hugo D Luján, Elmer A Fernández
- Front Immunol, 10.3389/fimmu.2023.1094236
Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy
- Barbara Sennino, Songming Peng, Clifford L Wang, …, Alex Franzusoff, Stefanie J Mandl, Antoni Ribas
- Nature, 10.1038/s41586-023-05787-1
Sensitive, High-Throughput HLA-I and HLA-II Immunopeptidomics Using Parallel Accumulation-Serial Fragmentation Mass Spectrometry
- Kshiti Meera Phulphagar, Claudia Ctortecka, Alvaro Sebastian Vaca Jacome, …, Karl R Clauser, Jennifer G Abelin, Steven A Carr
- Mol Cell Proteomics, 10.1016/j.mcpro.2023.100563
Usefulness of Docking and Molecular Dynamics in Selecting Tumor Neoantigens to Design Personalized Cancer Vaccines: A Proof of Concept
- Diego Amaya-Ramirez, Laura Camila Martinez-Enriquez, Carlos Parra-López, …, Diego Amaya-Ramirez, Laura Camila Martinez-Enriquez, Carlos Parra-López
- None, 10.3390/vaccines11071174
Computational prediction of MHC anchor locations guides neoantigen identification and prioritization
- Huiming Xia, Joshua McMichael, Michelle Becker-Hapak, …, Todd A Fehniger, Obi L Griffith, Malachi Griffith
- Sci Immunol, 10.1126/sciimmunol.abg2200
2022 Articles
164 articles
Identification of DDX60 as a Regulator of MHC-I Class Molecules in Colorectal Cancer
- Nina Geng, Tuo Hu, Chunbo He, Nina Geng, Tuo Hu, Chunbo He
- None, 10.3390/biomedicines10123092
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer
- Andrew Chow, Fathema Z Uddin, Michael Liu, …, Jedd D Wolchok, Taha Merghoub, Charles M Rudin
- Immunity, 10.1016/j.immuni.2022.12.001
Tumor cells fail to present MHC-II-restricted epitopes derived from oncogenes to CD4+ T cells
- Spencer E Brightman, Martin S Naradikian, Rukman R Thota, …, Ezra Ew Cohen, Aaron M Miller, Stephen P Schoenberger
- JCI Insight, 10.1172/jci.insight.165570
Recruiting T cells and sensitizing tumors to NKG2D immune surveillance for robust antitumor immune response
- Xiang Li, Xuemeng Guo, Jiaxin Huang, …, Fuchun Yang, Lihua Luo, Jian You
- J Control Release, 10.1016/j.jconrel.2022.12.032
Immunoinformatics Approach for Epitope-Based Vaccine Design: Key Steps for Breast Cancer Vaccine
- Aisyah Fitriannisa Prawiningrum, Rafika Indah Paramita, Sonar Soni Panigoro, Aisyah Fitriannisa Prawiningrum, Rafika Indah Paramita, Sonar Soni Panigoro
- None, 10.3390/diagnostics12122981
Disruption of the NKG2A:HLA-E Immune Checkpoint Axis to Enhance NK Cell Activation against Cancer
- Jack G Fisher, Amber D P Doyle, Lara V Graham, …, Lara V Graham, Salim I Khakoo, Matthew D Blunt
- None, 10.3390/vaccines10121993
Epigenetic reprogramming of carrier free photodynamic modulator to activate tumor immunotherapy by EZH2 inhibition
- Linping Zhao, Xiaona Rao, Chuyu Huang, …, Xiyong Yu, Hong Cheng, Shiying Li
- Biomaterials, 10.1016/j.biomaterials.2022.121952
Engineered cell entry links receptor biology with single-cell genomics
- Bingfei Yu, Quanming Shi, Julia A Belk, …, Mark M Davis, Ansuman T Satpathy, Howard Y Chang
- Cell, 10.1016/j.cell.2022.11.016
Bypassing anti-PD-(L)1 therapy: Mechanisms and management strategies
- Keywan Mortezaee, Jamal Majidpoor, Sajad Najafi, …, Jamal Majidpoor, Sajad Najafi, Davood Tasa
- Biomed Pharmacother, 10.1016/j.biopha.2022.114150
Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours
- Yuto Watanabe, Kenji Murata, Shuto Hamada, …, Munehide Nakatsugawa, Toshihiko Yamashita, Toshihiko Torigoe
- Br J Cancer, 10.1038/s41416-022-02100-1