Channel: Mitophagy

Mitophagy is the selective degradation of mitochondria by autophagy. It often occurs to defective mitochondria following damage or stress. Wikipedia (CC BY-SA 3.0)

2023 Articles

2 058 articles

Eating your mitochondria-when too much of a good thing turns bad

  • Léa P Wilhelm, Ian G Ganley, Léa P Wilhelm, …, Ian G Ganley, Léa P Wilhelm, Ian G Ganley
  • EMBO J, 10.15252/embj.2023114542
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Fine-tune TMEM11 to unleash basal mitophagy

  • Thomas G McWilliams, Thomas G McWilliams, Thomas G McWilliams, …, Thomas G McWilliams, Thomas G McWilliams, Thomas G McWilliams
  • J Cell Biol, 10.1083/jcb.202302118
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Michael J Clague: mitophagy, pexophagy, & metabolism

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The ER membrane protein complex governs lysosomal turnover of a mitochondrial tail-anchored protein, BNIP3, to restrict mitophagy

  • Jose M Delgado, Logan Wallace Shepard, Sarah W Lamson, …, Sarah W Lamson, Samantha L Liu, Christopher J Shoemaker
  • bioRxiv : the preprint server for biology, 10.1101/2023.03.22.533681
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Segregation of pathways leading to pexophagy

  • Francesco G Barone, Sylvie Urbé, Francesco G Barone, …, Francesco G Barone, Sylvie Urbé, Michael J Clague
  • Life Sci Alliance, 10.26508/lsa.202201825
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FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo

  • Alvaro Sanchez-Martinez, Aitor Martinez, Alexander J Whitworth, …, Alvaro Sanchez-Martinez, Aitor Martinez, Alexander J Whitworth
  • PLoS Biol, 10.1371/journal.pbio.3002244
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DRP1-Mediated Mitophagy: Safeguarding Obese Hearts From Cardiomyopathy

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Bendless is essential for PINK1-Park mediated Mitofusin degradation under mitochondrial stress caused by loss of LRPPRC

  • Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, …, Neha Singhal, Sonal Nagarkar Jaiswal, Manish Jaiswal
  • PLoS Genet, 10.1371/journal.pgen.1010493
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The mitophagy pathway and its implications in human diseases

  • Shouliang Wang, Haijiao Long, Lianjie Hou, …, Jiahao Cai, Da-Wei Zhang, Guojun Zhao
  • Signal Transduct Target Ther, 10.1038/s41392-023-01503-7
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UBQLN2 and HSP70 participate in Parkin-mediated mitophagy by facilitating outer mitochondrial membrane rupture

  • Qilian Ma, Jiaqi Xin, Qiang Peng, …, Jochen Hm Prehn, Hongfeng Wang, Zheng Ying
  • EMBO Rep, 10.15252/embr.202255859
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2022 Articles

197 articles

Diversity of mitophagy pathways at a glance

  • Ian G Ganley, Anne Simonsen, Ian G Ganley, Anne Simonsen, Ian G Ganley, Anne Simonsen
  • J Cell Sci, 10.1242/jcs.259748
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PINK1/Parkin-mediated mitophagy in neurodegenerative diseases

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FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagy

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Orchestration of selective autophagy by cargo receptors

  • Elias Adriaenssens, Luca Ferrari, Sascha Martens, …, Elias Adriaenssens, Luca Ferrari, Sascha Martens
  • Curr Biol, 10.1016/j.cub.2022.11.002
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Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid-liquid phase separation-based method

  • Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, …, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano
  • J Biol Chem, 10.1016/j.jbc.2022.102822
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Artemisinin Alleviates Cerebral Ischemia/Reperfusion-Induced Oxidative Damage via Regulating PHB2-Mediated Autophagy in the Human Neuroblastoma SH-SY5Y Cell Line

  • Menghan Jiang, Xiaoyi Lai, Yongjiang Zhang, …, Anran Liu, Jiannan Wu, Junqiang Yan
  • Oxid Med Cell Longev, 10.1155/2022/6568748
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Investigating mitochondrial fission, fusion, and autophagy in retinal pigment epithelium from donors with age-related macular degeneration

  • Cody R Fisher, Adam A Shaaeli, Mara C Ebeling, …, Mara C Ebeling, Sandra R Montezuma, Deborah A Ferrington
  • Sci Rep, 10.1038/s41598-022-26012-5
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Ginsenoside CK improves skeletal muscle insulin resistance by activating DRP1/PINK1-mediated mitophagy

  • Weili Li, Haiyang Li, Lujuan Zheng, …, Shuhan Men, Ye Yuan, Yuying Fan
  • Food Funct, 10.1039/d2fo02026b
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Mitochondrial quality control in the brain: The physiological and pathological roles

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Mitochondrial dynamics, elimination and biogenesis during post-ischemic recovery in ischemia-resistant and ischemia-vulnerable gerbil hippocampal regions

  • Maria Kawalec, Piotr Wojtyniak, Ewelina Bielska, …, MaÅ‚gorzata Frontczak-Baniewicz, Magdalena Gewartowska, Barbara ZabÅ‚ocka
  • Biochim Biophys Acta Mol Basis Dis, 10.1016/j.bbadis.2022.166633
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