Oxytosis/ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis. Oxytosis/ferroptosis is initiated by the failure of the glutathione-dependent antioxidant defenses, resulting in unchecked lipid peroxidation and eventual cell death. Wikipedia (CC BY-SA 3.0)
2023 Articles
3 433 articles
Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition
- Chao Mao, Xiaoguang Liu, Yuelong Yan, …, Yuelong Yan, Kellen Olszewski, Boyi Gan
- Nature, 10.1038/s41586-023-06270-7
cGASing mitochondria to fend off ferroptosis
- Hua Wang, Hua Wang, Hua Wang, …, Xuejun Jiang, Hua Wang, Xuejun Jiang
- Cell Res, 10.1038/s41422-023-00791-6
Ferroptosis in mitochondrial cardiomyopathy
- Sofia Ahola, Thomas Langer
- Trends Cell Biol, 10.1016/j.tcb.2023.06.002
Promotion of ferroptosis in head and neck cancer with divalent metal transporter 1 inhibition or salinomycin
- Jaewang Lee, Jaewang Lee, Jaewang Lee, Jaewang Lee, Jong-Lyel Roh
- Hum Cell, 10.1007/s13577-023-00890-x
USP11-mediated LSH deubiquitination inhibits ferroptosis in colorectal cancer through epigenetic activation of CYP24A1
- Junyi Duan, Daoyuan Huang, Cheng Liu, …, Li Li, Weiping Wang, Genze Shao
- Cell Death Dis, 10.1038/s41419-023-05915-9
FSP1 confers ferroptosis resistance in KEAP1 mutant non-small cell lung carcinoma in NRF2-dependent and -independent manner
- Jong Woo Kim, Min-Ju Kim, Tae-Hee Han, …, Sang Chul Lee, Haeseung Lee, Eun-Woo Lee
- Cell Death Dis, 10.1038/s41419-023-06070-x
Molecular characterization of AIFM2/FSP1 inhibition by iFSP1-like molecules
- Thamara Nishida Xavier da Silva, Clemens Schulte, Ariane Nunes Alves, …, Ariane Nunes Alves, Hans Michael Maric, José Pedro Friedmann Angeli
- Cell Death Dis, 10.1038/s41419-023-05787-z
Ferroptosis model system by the re-expression of BACH1
- Riko Irikura, Hironari Nishizawa, Kazuma Nakajima, …, Masafumi Onodera, Mitsuyo Matsumoto, Kazuhiko Igarashi
- J Biochem, 10.1093/jb/mvad036
A catalase inhibitor: Targeting the NADPH-binding site for castration-resistant prostate cancer therapy
- Ya Ya Cao, Yuan Yuan Chen, Ming Shu Wang, …, Wei Huang, Dan Zhang, Guang Fu Yang
- Redox Biol, 10.1016/j.redox.2023.102751
ATM orchestrates ferritinophagy and ferroptosis by phosphorylating NCOA4
- Hao Wu, Qian Liu, Xinyi Shan, …, Xinyi Shan, Weihua Gao, Quan Chen
- Autophagy, 10.1080/15548627.2023.2170960
2022 Articles
359 articles
An iron-dependent form of non-canonical ferroptosis induced by labile iron
- Yanmeng Li, Qin Ouyang, Wei Chen, …, Junying Ding, Min Cong, Anjian Xu
- Sci China Life Sci, 10.1007/s11427-022-2244-4
Recent progress in ferroptosis: inducers and inhibitors
- Yunxi Du, Yunxi Du, Yunxi Du, Yunxi Du, Yunxi Du, Zhong Guo
- Cell Death Dis, 10.1038/s41420-022-01297-7
Induction of ferroptosis by HO-1 contributes to retinal degeneration in mice with defective clearance of all-trans-retinal
- Chao Chen, Kunhuan Yang, Danxue He, …, Lei Tao, Jingmeng Chen, Yalin Wu
- Free Radic Biol Med, 10.1016/j.freeradbiomed.2022.12.008
Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis
- Nora Hanke, Abdelhaq Rami, Nora Hanke, Abdelhaq Rami, Nora Hanke, Abdelhaq Rami
- None, 10.4103/1673-5374.360246
New perspectives on ferroptosis and its role in hepatocellular carcinoma
- Tianhao Cong, Yingen Luo, Yan Fu, …, Yu Liu, Yujie Li, Xiao Li
- Chin Med J (Engl), 10.1097/cm9.0000000000002327
Mitochondrial Calcium Homeostasis in the Pathology and Therapeutic Application in Friedreich’s Ataxia
- Hongting Zhao, Zhuoyuan Li, Yutong Liu, …, Yutong Liu, Meng Zhang, Kuanyu Li
- Neurosci Bull, 10.1007/s12264-022-01007-4
Baicalein and luteolin inhibit ischemia/reperfusion-induced ferroptosis in rat cardiomyocytes
- I-Chieh Wang, Jian-Hong Lin, Wen-Sen Lee, …, Chin-Hung Liu, Ting-Yuan Lin, Kun-Ta Yang
- Int J Cardiol, 10.1016/j.ijcard.2022.12.018
Simultaneous regulation of ferroptosis suppressor protein 1 and glutathione peroxidase 4 as a new therapeutic strategy of ferroptosis for esophageal squamous cell carcinoma
- Yuji Shishido, Yoshiaki Matsumi, Tomoyuki Matsunaga, …, Yoshihisa Umekita, Toshimichi Hasegawa, Yoshiyuki Fujiwara
- Esophagus, 10.1007/s10388-022-00982-x
Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics
- Ying-Ming Chu, Ting-Xin Wang, Xiao-Fen Jia, …, Qiu-Yue Huang, Hui Ye, Xue-Zhi Zhang
- None, 10.3389/fphar.2022.1066244
Inducing ferroptosis has the potential to overcome therapy resistance in breast cancer
- Xiaowen Qi, Zhixing Wan, Baohong Jiang, …, Rongfang He, Liming Xie, Yuehua Li
- Front Immunol, 10.3389/fimmu.2022.1038225