Proteostasis is the homeostatic process of maintaining all the proteins necessary for the functioning of the cell in their proper shape, structure and abundance. Protein misfolding, oxidation, abnormal cleavage or undesired post-translational modification can create dysfunctional or even toxic proteins or protein aggregates that hinder the normal functioning of the cell Wikipedia (CC BY-SA 3.0)
2023 Articles
138 196 articles
GDF-11 as a Potential Cardiac Pro-Angiogenic Factor
- Tomohiro Kato, Richard T Lee, Tomohiro Kato, Richard T Lee, Tomohiro Kato, Richard T Lee
- None, 10.1016/j.jacbts.2023.04.003
Immunofluorescence and Aggresome Staining of Nothobranchius furzeri Cryosections
- Sara Bagnoli, Eva Terzibasi Tozzini, Alessandro Cellerino, …, Sara Bagnoli, Eva Terzibasi Tozzini, Alessandro Cellerino
- Cold Spring Harb Protoc, 10.1101/pdb.prot107791
Putting aging on ICE
- Bryan B Teefy, BĂ©rĂ©nice A Benayoun, Bryan B Teefy, …, BĂ©rĂ©nice A Benayoun, Bryan B Teefy, BĂ©rĂ©nice A Benayoun
- Cell Metab, 10.1016/j.cmet.2023.02.012
miR-126-5p affects the chemosensitivity of colorectal cancer cells by regulating SPRED1, ERK1/2 pathway and apoptosis
- Mingshi Xu, Gang Zhang, Xiaofan Gu, …, Fangqin Zhao, Zhongmin Yang, Xiongwen Zhang
- None, 10.1016/j.gendis.2022.05.024
Transferrin receptor 1: keeper of HFE
- Nermi L Parrow, Robert E Fleming, Nermi L Parrow, …, Robert E Fleming, Nermi L Parrow, Robert E Fleming
- Blood, 10.1182/blood.2022018740
What the Stanford president’s resignation can teach lab leaders
- Max Kozlov, Max Kozlov
- Nature, 10.1038/d41586-023-02438-3
Deciphering dynamic changes of the aging transcriptome with COVID-19 progression and convalescence in the human blood
- Ran Li, Jing Zou, Dongling Pei, …, Yan Chen, Fangfang Zhou, Long Zhang
- Signal Transduct Target Ther, 10.1038/s41392-023-01466-9
2022 Articles
15 921 articles
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
- Wendao Liu, Xiaohua Ye, Zhiqiang An, …, Xiaohua Ye, Zhiqiang An, Zhongming Zhao
- Virol J, 10.1186/s12985-022-01923-x
Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals
- Natalia Mota-Martorell, Mariona JovĂ©, Rebeca BerdĂșn, …, Ălia Ăbis, Gustavo Barja, Reinald Pamplona
- None, 10.3390/biology11121821
A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging
- Tibor KovĂĄcs, Janka SzinyĂĄkovics, Viktor Billes, …, KĂĄroly Gulya, ZsĂłfia MaglĂłczky, Tibor Vellai
- Sci Rep, 10.1038/s41598-022-24843-w
Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial
- Florian Kurth, Elisa T Helbig, Lena J Lippert, …, Leif E Sander, Christoph Jochum, Frank Tacke
- J Glob Antimicrob Resist, 10.1016/j.jgar.2022.12.004
Identification of Apolipoprotein D as a Dermal Fibroblast Marker of Human Aging for Development of Skin Rejuvenation Therapy
- Kento Takaya, Toru Asou, Kazuo Kishi, …, Kento Takaya, Toru Asou, Kazuo Kishi
- Rejuvenation Res, 10.1089/rej.2022.0056
Aging reduces ABHD5 protein content in the adipose tissue of mice: The reversal effect of exercise
- Rafael S BrĂcola, AndrĂ© V Cordeiro, Barbara M Crisol, …, JosĂ© R Pauli, Dennys E Cintra, Eduardo R Ropelle
- Cell Biochem Funct, 10.1002/cbf.3770
The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster
- Kaniz Fatima Binte Hossain, Anjaneyulu Murari, Bibhuti Mishra, …, Anjaneyulu Murari, Bibhuti Mishra, Edward Owusu-Ansah
- Sci Rep, 10.1038/s41598-022-26414-5
Senescence induces proteolytically-active PAPP-A secretion and association with extracellular vesicles in human pre-adipocytes
- Cheryl A Conover, Laurie K Bale, Cheryl A Conover, …, Laurie K Bale, Cheryl A Conover, Laurie K Bale
- Exp Gerontol, 10.1016/j.exger.2022.112070
Muscle Delivery of Mitochondria-Targeted Drugs for the Treatment of Sarcopenia: Rationale and Perspectives
- Francesco Bellanti, Aurelio Lo Buglio, Gianluigi Vendemiale, …, Francesco Bellanti, Aurelio Lo Buglio, Gianluigi Vendemiale
- None, 10.3390/pharmaceutics14122588
Eucommia ulmoides male flower as a remarkable edible floral resource exerts lifespan/healthspan-promoting effects on Caenorhabditis elegans
- Qi Chen, Xuan Yang, Esra Capanoglu, …, Xiongtao Jiang, Dayong Zhang, Baiyi Lu
- Food Funct, 10.1039/d2fo03006c