Channel: Knee osteoarthritis

Knee osteoarthritis is a type of degenerative joint disease in the knee that results from breakdown of joint cartilage and underlying bone. Wikipedia (CC BY-SA 3.0)

2023 Articles

1 364 articles

Urchin-like ceria nanoparticles for enhanced gene therapy of osteoarthritis

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Association of dipeptidylpeptidase 4 (CD26) with chondrocyte senescence and radiographic progression in knee osteoarthritis: comment on the article by Chen et al

  • An-Fang Huang, Wang-Dong Xu, An-Fang Huang, …, Wang-Dong Xu, An-Fang Huang, Wang-Dong Xu
  • Arthritis Rheumatol, 10.1002/art.42490
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Intra-articular injection of rapamycin microparticles prevent senescence and effectively treat osteoarthritis

  • Kaamini M Dhanabalan, Ameya A Dravid, Smriti Agarwal, …, Ramanath K Sharath, Ashok Kumar Padmanabhan, Rachit Agarwal
  • None, 10.1002/btm2.10298
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Activated macrophage membrane-coated nanoparticles relieve osteoarthritis-induced synovitis and joint damage

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Long Non-coding RNA SNHG7 Suppresses Inflammation and Apoptosis of Chondrocytes Through Inactivating of p38 MAPK Signaling Pathway in Osteoarthritis

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Recent Advances in Small Molecule Inhibitors for the Treatment of Osteoarthritis

  • Jianjing Lin, Shicheng Jia, Weifei Zhang, …, Wei Li, Hui Zeng, Xintao Zhang
  • None, 10.3390/jcm12051986
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Articular Cartilage Regeneration via Induced Chondrocyte Autophagy by Sustained Release of Leptin Inhibitor from Thermo-Sensitive Hydrogel Through STAT3/REDD1/mTORC1 Cascade

  • Zhongming Huang, Chen Liu, Guangping Zheng, …, Yun Zhang, Weicheng Zhao, Yiying Qi
  • Adv Healthc Mater, 10.1002/adhm.202302181
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Bauhinia championii alleviates extracellular matrix degradation in IL-1β induced chondrocytes via miRNA-145-5p/TLR4/NF-κB axis

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Mechanism of HIFs in osteoarthritis

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Natural Compounds: Potential Therapeutics for the Inhibition of Cartilage Matrix Degradation in Osteoarthritis

  • Omer S Ashruf, Mohammad Yunus Ansari, Omer S Ashruf, …, Mohammad Yunus Ansari, Omer S Ashruf, Mohammad Yunus Ansari
  • None, 10.3390/life13010102
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2022 Articles

185 articles

Co-Polymer Carrier with Dual Advantages of Cartilage-Penetrating and Targeting Improves Delivery and Efficacy of MicroRNA Treatment of Osteoarthritis

  • Yipu Zhao, Xudong Deng, Shenxing Tan, …, Dachuan Yin, Ye Tian, Airong Qian
  • Adv Healthc Mater, 10.1002/adhm.202202143
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Intra-articular injection of rAAV-hFGF-2 ameliorates monosodium iodoacetate-induced osteoarthritis in rats via inhibiting TLR-4 signaling and activating TIMP-1

  • Mostafa A Rabie, Rabab H Sayed, Jagadeesh K Venkatesan, …, Henning Madry, Magali Cucchiarini, Nesrine S El Sayed
  • Toxicol Appl Pharmacol, 10.1016/j.taap.2022.116361
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Focusing on the hypoxia-inducible factor pathway: role, regulation, and therapy for osteoarthritis

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Polymeric Nanoparticles for Drug Delivery in Osteoarthritis

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A Fenchone Derivative Effectively Abrogates Joint Damage Following Post-Traumatic Osteoarthritis in Lewis Rats

  • Idan Carmon, Reem Smoum, Eli Farhat, …, Ruth Gallily, Raphael Mechoulam, Mona Dvir-Ginzberg
  • Cells, 10.3390/cells11244084
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MicroRNAs and long non-coding RNAs in cartilage homeostasis and osteoarthritis

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Dapansutrile ameliorated chondrocyte inflammation and osteoarthritis through suppression of MAPK signaling pathway

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Promotion of Knee Cartilage Degradation by IκB Kinase ε in the Pathogenesis of Osteoarthritis in Human and Murine Models

  • Taisuke Uchida, Yukio Akasaki, Takuya Sueishi, …, Hidetoshi Tsushima, Martin K Lotz, Yasuharu Nakashima
  • Arthritis Rheumatol, 10.1002/art.42421
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Indirubin protects chondrocytes and alleviates OA by inhibiting the MAPK and NF-κB pathways

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Genetic influences of the effect of circulating inflammatory cytokines on osteoarthritis in humans

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