Inflammaging (also known as inflamm-aging or inflamm-ageing) is a chronic, sterile, low-grade inflammation that develops with advanced age, in the absence of overt infection, and may contribute to clinical manifestations of other age-related pathologies. Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in chronic, overstimulation of the innate immune system. Inflammaging is a significant risk factor in mortality and morbidity in aged individuals. Wikipedia (CC BY-SA 3.0)
2023 Articles
76 405 articles
Clonal hematopoiesis and ischemic stroke
- Nan Wang, Alan R Tall, Nan Wang, …, Alan R Tall, Nan Wang, Alan R Tall
- Blood, 10.1182/blood.2022019177
Resilient brains run out of (c)GAS
- Andrea Francesca M Salvador, Andrea Francesca M Salvador, Andrea Francesca M Salvador, …, Jonathan Kipnis, Andrea Francesca M Salvador, Jonathan Kipnis
- Nat Immunol, 10.1038/s41590-023-01485-2
Gut microbes modulate neurodegeneration
- Tanya Jain, Yue-Ming Li, Tanya Jain, …, Yue-Ming Li, Tanya Jain, Yue-Ming Li
- Science, 10.1126/science.adf9548
FAP senescence: a critical event in muscle regeneration
- Xia Kang, Yuqi Gao, So-Ichiro Fukada, …, Yuqi Gao, So-Ichiro Fukada, Hongming Miao
- Signal Transduct Target Ther, 10.1038/s41392-023-01411-w
A gut reaction can tune tumour fate during chemotherapy
- Le Li, Florencia McAllister, Le Li, …, Florencia McAllister, Le Li, Florencia McAllister
- Nature, 10.1038/d41586-023-00476-5
Exaggerated responses to a virus long gone
- Petter Brodin, Petter Brodin, Petter Brodin
- Science, 10.1126/science.adg2776
Murine studies and expressional analyses of human cardiac pericytes reveal novel trajectories of SARS-CoV-2 Spike protein-induced microvascular damage
- Elisa Avolio, Prashant K Srivastava, Jiahui Ji, …, Imre Berger, Costanza Emanueli, Paolo Madeddu
- Signal Transduct Target Ther, 10.1038/s41392-023-01489-2
Genetic variant in complement receptor 1 (CR1, CD35) is associated with a cluster of severe fatal COVID-19 in a family
- N Danial-Farran, M Khlaila, M Avraham-Kelbert, …, A Winder, S Shalev, N Bisharat
- J Infect, 10.1016/j.jinf.2023.03.014
High-resolution aging niche of human adipose tissues
- Wenyan Zhou, Junxin Lin, Yan Xie, …, Aaron Trent Irving, James Q Wang, Hongwei Ouyang
- Signal Transduct Target Ther, 10.1038/s41392-023-01315-9
Recent insights into the crosstalk between senescent cells and CD8 T lymphocytes
- Ines Marin, Ines Marin, Ines Marin, Ines Marin, Manuel Serrano, Federico Pietrocola
- None, 10.1038/s41514-023-00105-5
2022 Articles
9 114 articles
Gutsy sensations modulate intestinal disease
- Wang Cao, Gabrielle Belz, Wang Cao, …, Gabrielle Belz, Wang Cao, Gabrielle Belz
- Trends Immunol, 10.1016/j.it.2022.11.007
The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation
- Wendao Liu, Xiaohua Ye, Zhiqiang An, …, Xiaohua Ye, Zhiqiang An, Zhongming Zhao
- Virol J, 10.1186/s12985-022-01923-x
Cenicriviroc for the treatment of COVID-19: first interim results of a randomised, placebo-controlled, investigator-initiated, double-blind phase II trial
- Florian Kurth, Elisa T Helbig, Lena J Lippert, …, Leif E Sander, Christoph Jochum, Frank Tacke
- J Glob Antimicrob Resist, 10.1016/j.jgar.2022.12.004
Synergism of TNF-α and IFN-β triggers human airway epithelial cells death by apoptosis and pyroptosis
- Rui Sun, Kaimin Jiang, Chengyue Zeng, …, Hanyu Chu, Huiyong Liu, Jingchun Du
- Mol Immunol, 10.1016/j.molimm.2022.12.002
Rigid respiration: fulminant pulmonary fibrosis after COVID-19
- David K Meyerholz, David K Meyerholz, David K Meyerholz, …, David K Meyerholz, David K Meyerholz, David K Meyerholz
- EBioMedicine, 10.1016/j.ebiom.2022.104428
Brain borders at the central stage of neuroimmunology
- Justin Rustenhoven, Justin Rustenhoven, Justin Rustenhoven, …, Jonathan Kipnis, Justin Rustenhoven, Jonathan Kipnis
- Nature, 10.1038/s41586-022-05474-7
Are aged pTreg cells “the more the better”?
- Weikan Wang, Rachel Thomas, Dong-Ming Su, …, Weikan Wang, Rachel Thomas, Dong-Ming Su
- Aging (Albany NY), 10.18632/aging.204454
Frequency of IRF5+ dendritic cells is associated with the TLR7-induced inflammatory cytokine response in SARS-CoV-2 infection
- Leon Cords, Robin Woost, Silke Kummer, …, Marylyn M Addo, Julian Schulze Zur Wiesch, Claudia Beisel
- Cytokine, 10.1016/j.cyto.2022.156109
Response by Sedej and Abdellatif to Letter Regarding Article, “Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity”
- Simon Sedej, Mahmoud Abdellatif, Simon Sedej, Mahmoud Abdellatif, Simon Sedej, Mahmoud Abdellatif
- Circulation, 10.1161/circulationaha.122.062496
The age-dependent immune response to ischemic stroke
- Mary Claire Tuohy, Elizabeth M C Hillman, Randolph Marshall, …, Elizabeth M C Hillman, Randolph Marshall, Dritan Agalliu
- Curr Opin Neurobiol, 10.1016/j.conb.2022.102670