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2023 Articles
31 942 articles
CIP2A and TOPBP1: Molecular lassos that herd pulverized micronuclear chromosomes
- Chaithanya P Vedula, Neil J Ganem, Chaithanya P Vedula, Neil J Ganem, Chaithanya P Vedula, Neil J Ganem
- Mol Cell, 10.1016/j.molcel.2023.05.032
Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis
- Venus Marie Gaela, Liuh-Yow Chen, Venus Marie Gaela, …, Liuh-Yow Chen, Venus Marie Gaela, Liuh-Yow Chen
- Mol Cell, 10.1016/j.molcel.2023.03.012
Synthetic biology, genetic circuits and machine learning: a new age of cancer therapy
- Krishneel Prasad, Ryan S Cross, Misty R Jenkins, …, Krishneel Prasad, Ryan S Cross, Misty R Jenkins
- Mol Oncol, 10.1002/1878-0261.13420
A lack of commitment to proliferation
- Alexis R Barr, Alexis R Barr, Alexis R Barr, Alexis R Barr, Alexis R Barr
- Nature, 10.1038/d41586-023-02136-0
High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells
- Florian J Groelly, Rebecca A Dagg, Jonathan Mailler, …, Jonathan Mailler, Thanos D Halazonetis, Madalena Tarsounas
- STAR Protoc, 10.1016/j.xpro.2022.101970
Targeting the undruggable
- Samuel F Bakhoum, Samuel F Bakhoum, Samuel F Bakhoum
- Science, 10.1126/science.adg7671
Mitotic tethering enables inheritance of shattered micronuclear chromosomes
- Prasad Trivedi, Christopher D Steele, Franco K C Au, …, Franco K C Au, Ludmil B Alexandrov, Don W Cleveland
- Nature, 10.1038/s41586-023-06216-z
T cell TET2 disruption cuts the breaks on antitumor CAR T cell therapy
- Caitlin C Zebley, Ben Youngblood, Caitlin C Zebley, …, Ben Youngblood, Caitlin C Zebley, Ben Youngblood
- Trends Immunol, 10.1016/j.it.2023.03.008
The KaryoCreate technology generates specific aneuploid karyotypes on demand
- Annapaola Angrisani, Daniele Fachinetti, Annapaola Angrisani, Daniele Fachinetti, Annapaola Angrisani, Daniele Fachinetti
- Cell Rep Methods, 10.1016/j.crmeth.2023.100514
MYC retards cancer cell migration through suppressing fibronectin expression
- Mengjia Zhao, Peng Jiang, Wenjing Du
- Sci Bull (Beijing), 10.1016/j.scib.2019.04.027
2022 Articles
3 528 articles
Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights
- Mingzheng Hu, Yijie Wang, Jun Zhou, Mingzheng Hu, Yijie Wang, Jun Zhou
- None, 10.1097/bs9.0000000000000127
Epigenetic clocks, aging, and cancer
- Sarah E Johnstone, Vadim N Gladyshev, Martin J Aryee, …, Vadim N Gladyshev, Martin J Aryee, Bradley E Bernstein
- Science, 10.1126/science.abn4009
Bicarbonate transport as a vulnerability in pancreatic cancer
- Li Qiang, Li Qiang, Li Qiang, …, Stephanie K Dougan, Li Qiang, Stephanie K Dougan
- Nat Cancer, 10.1038/s43018-022-00492-w
Expression dynamics of periodic transcripts during cancer cell cycle progression and their correlation with anticancer drug sensitivity
- Chun-Xiao Li, Jin-Song Wang, Wen-Na Wang, …, Bing-He Xu, Fei Ma, Hai-Li Qian
- Mil Med Res, 10.1186/s40779-022-00432-w
Overexpressed c-Myc Sensitizes Cells to TH1579, a Mitotic Arrest and Oxidative DNA Damage Inducer
- Sofia Henriksson, José Manuel Calderón-Montaño, Daniel Solvie, …, Daniel Solvie, Ulrika Warpman Berglund, Thomas Helleday
- Biomolecules, 10.3390/biom12121777
Inhibition of p21 activates Akt kinase to trigger ROS-induced autophagy and impacts on tumor growth rate
- Mayank Maheshwari, Nisha Yadav, Mohammad Hasanain, …, Kalyan Mitra, Dipak Datta, Jayanta Sarkar
- Cell Death Dis, 10.1038/s41419-022-05486-1
Inactivation of KDM5A suppresses growth and enhances chemosensitivity in liver cancer by modulating ROCK1/PTEN/AKT pathway
- Shiji Fang, Liyun Zheng, Lin Shen, …, Zhongwei Zhao, Jianfei Tu, Jiansong Ji
- Eur J Pharmacol, 10.1016/j.ejphar.2022.175465
Increased replication origin firing links replication stress to whole chromosomal instability in human cancer
- Nicolas Böhly, Ann-Kathrin Schmidt, Xiaoxiao Zhang, …, Magdalena Hennecke, Maik Kschischo, Holger Bastians
- Cell Rep, 10.1016/j.celrep.2022.111836
BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms
- Anita Singh, Sara Busacca, Aarti Gaba, …, Alan G Dawson, Dean A Fennell, Andrew M Fry
- Oncogene, 10.1038/s41388-022-02577-3
Adaptation to high rates of chromosomal instability and aneuploidy through multiple pathways in budding yeast
- Matthew N Clarke, Theodor Marsoner, Manuel Alonso Y Adell, …, Manuel Alonso Y Adell, Madhwesh C Ravichandran, Christopher S Campbell
- EMBO J, 10.15252/embj.2022111500