Channel: Interleukin 6

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Wikipedia (CC BY-SA 3.0)

2023 Articles

41 639 articles

FAP senescence: a critical event in muscle regeneration

  • Xia Kang, Yuqi Gao, So-Ichiro Fukada, …, Yuqi Gao, So-Ichiro Fukada, Hongming Miao
  • Signal Transduct Target Ther, 10.1038/s41392-023-01411-w
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Clonal hematopoiesis and ischemic stroke

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“Prenatal programming of the brain: The maternal-fetal interface takes center stage”

  • Adrienne M Antonson, Adrienne M Antonson, Adrienne M Antonson, …, Adrienne M Antonson, Adrienne M Antonson, Adrienne M Antonson
  • Brain Behav Immun, 10.1016/j.bbi.2023.01.019
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Establishment of a novel protocol for formalin-fixed paraffin embedded organoids and spheroids

  • Shohei Yoshimoto, Masahide Taguchi, Satoko Sumi, …, Satoko Sumi, Kyoko Oka, Kazuhiko Okamura
  • Biol Open, 10.1242/bio.059882
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Commentary on “Novel Genetic Regulators of Fibrinogen Synthesis Identified by an In Vitro Experimental Platform”

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Clonal hematopoiesis, aging and Alzheimer’s disease

  • Pablo SĆ”nchez Vela, Jennifer J Trowbridge, Pablo SĆ”nchez Vela, …, Pablo SĆ”nchez Vela, Jennifer J Trowbridge, Ross L Levine
  • Nat Med, 10.1038/s41591-023-02406-4
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IL-6/gp130 signaling: a key unlocking regeneration

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Breaking the CH inflammation-expansion cycle

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IL-6-GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models

  • Marisa Carbonaro, Kehui Wang, Hui Huang, …, Mark Sleeman, Gavin Thurston, Zhe Li
  • Sci Adv, 10.1126/sciadv.adf4490
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Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes

  • Puyan Rafii, Christiane Seibel, Hendrik T Weitz, …, Karl Kƶhrer, Jens M Moll, JĆ¼rgen Scheller
  • Commun Biol, 10.1038/s42003-023-04768-4
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2022 Articles

4 971 articles

Variation in IL6ST cytokine family function and the potential of IL6 trans-signalling in ERĪ± positive breast cancer cells

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MiR-193-3p inhibits the malignant progression of atherosclerosis by targeting WDR5

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Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy

  • Rui Wang, Shuyun Zhao, Xiaojuan Chen, …, Shixiang Li, Hui Cheng, Guanyou Huang
  • BMC Pregnancy Childbirth, 10.1186/s12884-022-05307-5
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The Role of MRE11 in the IL-6/STAT3 Pathway of Lung Cancer Cells

  • Ching-Yuan Wu, Li-Hsin Shu, Hung-Te Liu, …, Yu-Ching Cheng, Yu-Huei Wu, Yu-Heng Wu
  • None, 10.3390/cimb44120418
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TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1Ī±

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Ergogenic effects of caffeine are mediated by myokines

  • Shingo Takada, Yoshizuki Fumoto, Shintaro Kinugawa, Shingo Takada, Yoshizuki Fumoto, Shintaro Kinugawa
  • None, 10.3389/fspor.2022.969623
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Role of STAT3 and NRF2 in Tumors: Potential Targets for Antitumor Therapy

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Infection and chronic disease activate a brain-muscle signaling axis that regulates muscle performance

  • Shuo Yang, Meijie Tian, Yulong Dai, …, Wanbo Tai, Gong Cheng, Aaron Johnson
  • bioRxiv : the preprint server for biology, 10.1101/2020.12.20.423533
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miR-216b-5p regulates proliferation and apoptosis of ox-LDL-stimulated VSMCs and HUVECs via IGF2

  • Chuan Qu, Xin Liu, Xueyu Han, …, Meng Sun, Haixia Liu, Bo Yang
  • J Biochem Mol Toxicol, 10.1002/jbt.23271
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Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells

  • Giada Lodi, Valentina Gentili, Fabio Casciano, …, Mercedes Fernandez, Roberta Rizzo, Rebecca Voltan
  • None, 10.3389/fphar.2022.1018761
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