The profile of where, when and to what extent these modifications occur to the epigenome changes with aging, turning useful genes off and unnecessary ones on, disrupting the normal functioning of the cell. Wikipedia (CC BY-SA 3.0)
2023 Articles
58 590 articles
The loss of epigenetic information: not only consequences but a cause of mammalian aging
- Chen Pan, Chen Pan, Chen Pan, …, Chen Pan, Fangfang Zhou, Long Zhang
- Signal Transduct Target Ther, 10.1038/s41392-023-01412-9
Putting aging on ICE
- Bryan B Teefy, BĂ©rĂ©nice A Benayoun, Bryan B Teefy, …, BĂ©rĂ©nice A Benayoun, Bryan B Teefy, BĂ©rĂ©nice A Benayoun
- Cell Metab, 10.1016/j.cmet.2023.02.012
Frontiers in aging special issue: DNA repair and interventions in aging perspective on “loss of epigenetic information as a cause of mammalian aging”
- Ethan D Schaffer, Isabel Beerman, Rafael de Cabo, …, Isabel Beerman, Rafael de Cabo, Robert M Brosh
- None, 10.3389/fragi.2023.1199596
LONRF2 exerts protein quality control in ageing neurons
- Heather Wood
- Nat Rev Neurol, 10.1038/s41582-023-00859-2
Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis
- Auyon J Ghosh, Matthew Moll, Brian D Hobbs, …, Edwin K Silverman, Ivana V Yang, Craig P Hersh
- Am J Respir Crit Care Med, 10.1164/rccm.202209-1835le
Awakening of ancient retrovirus: a new sign of aging in humans?
- Yuliang Qu, Jichang Wang, Yuliang Qu, …, Jichang Wang, Yuliang Qu, Jichang Wang
- Sci China Life Sci, 10.1007/s11427-023-2303-x
Mammalian aging driven by transcription going awry
- Brenna S McCauley, Weiwei Dang
- Trends Genet, 10.1016/j.tig.2023.06.006
T cell TET2 disruption cuts the breaks on antitumor CAR T cell therapy
- Caitlin C Zebley, Ben Youngblood, Caitlin C Zebley, …, Ben Youngblood, Caitlin C Zebley, Ben Youngblood
- Trends Immunol, 10.1016/j.it.2023.03.008
Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease
- Alessio Butera, Lena Smirnova, Elisa Ferrando-May, …, Thomas Brunner, Marcel Leist, Ivano Amelio
- EMBO Mol Med, 10.15252/emmm.202318208
2022 Articles
6 483 articles
Single short reprogramming early in life increases healthspan
- Jean-Marc Lemaitre, Ollivier Milhavet, Ollivier Milhavet, …, Jean-Marc Lemaitre, Ollivier Milhavet, Jean-Marc Lemaitre
- Aging (Albany NY), 10.18632/aging.204457
Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue
- Megha Murthy, Gemma Shireby, Yasuo Miki, …, Thomas T Warner, Jonathan Mill, Conceição Bettencourt
- Neuropathol Appl Neurobiol, 10.1111/nan.12872
DNA methylation GrimAge version 2
- Ake T Lu, Alexandra M Binder, Joshua Zhang, …, Luigi Ferrucci, Riccardo E Marioni, Steve Horvath
- Aging (Albany NY), 10.18632/aging.204434
Epigenetic clocks, aging, and cancer
- Sarah E Johnstone, Vadim N Gladyshev, Martin J Aryee, …, Vadim N Gladyshev, Martin J Aryee, Bradley E Bernstein
- Science, 10.1126/science.abn4009
Epigenetic clocks provide clues to the mystery of uterine ageing
- Pavel I Deryabin, Aleksandra V Borodkina, Pavel I Deryabin, Aleksandra V Borodkina, Pavel I Deryabin, Aleksandra V Borodkina
- Hum Reprod Update, 10.1093/humupd/dmac042
A Targeted Epigenetic Clock for the Prediction of Biological Age
- NoĂ©mie Gensous, Claudia Sala, Chiara Pirazzini, …, Claudio Franceschi, Maria Giulia Bacalini, Paolo Garagnani
- Cells, 10.3390/cells11244044
The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging
- Ana I Hernandez Cordero, Chen Xi Yang, Xuan Li, …, Shu Fan Paul Man, Don D Sin, Janice M Leung
- None, 10.3390/biomedicines10123094
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle
- Ronald G Jones, Andrea Dimet-Wiley, Amin Haghani, …, Stanley J Watowich, Christopher S Fry, Kevin A Murach
- J Physiol, 10.1113/jp283836
Methionine Metabolism Is Down-Regulated in Heart of Long-Lived Mammals
- Natalia Mota-Martorell, Mariona JovĂ©, Rebeca BerdĂșn, …, Ălia Ăbis, Gustavo Barja, Reinald Pamplona
- None, 10.3390/biology11121821
METTL3 and METTL14-mediated N6-methyladenosine modification promotes cell proliferation and invasion in a model of endometriosis
- Licong Shen, Chun Zhang, Yi Zhang, …, Chun Zhang, Yi Zhang, Yongwen Yang
- Reprod Biomed Online, 10.1016/j.rbmo.2022.10.010