Channel: Epigenetic ageing clocks

Inspired by: Steve Horvath

An epigenetic clock is a biochemical test that can be used to measure age. The test is based on DNA methylation levels, measuring the accumulation of methyl groups to one's DNA molecules. Wikipedia (CC BY-SA 3.0)

2023 Articles

36 940 articles

Putting aging on ICE

  • Bryan B Teefy, Bérénice A Benayoun, Bryan B Teefy, …, Bérénice A Benayoun, Bryan B Teefy, Bérénice A Benayoun
  • Cell Metab, 10.1016/j.cmet.2023.02.012
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Variability in MUC5B Expression Is Dependent on Genotype and Endotype in Idiopathic Pulmonary Fibrosis

  • Auyon J Ghosh, Matthew Moll, Brian D Hobbs, …, Edwin K Silverman, Ivana V Yang, Craig P Hersh
  • Am J Respir Crit Care Med, 10.1164/rccm.202209-1835le
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Epigenetic clocks suggest accelerated aging in patients with isolated REM Sleep Behavior Disorder

  • Luca Baldelli, Chiara Pirazzini, Luisa Sambati, …, Paolo Garagnani, Maria Giulia Bacalini, Federica Provini
  • None, 10.1038/s41531-023-00492-2
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Unravelling 2022: the 15th volume of Epigenomics

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Reply to: Comments on “Methylation scores for smoking, alcohol consumption and body mass index and risk of seven types of cancer”

  • Pierre-Antoine Dugué, Chenglong Yu, Allison M Hodge, …, Roger L Milne, Graham G Giles, Melissa C Southey
  • Int J Cancer, 10.1002/ijc.34644
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Challenges in anti-aging medicine-trends in biomarker discovery and therapeutic interventions for a healthy lifespan

  • Iuliana Popescu, Joris Deelen, Maddalena Illario, Jan Adams
  • J Cell Mol Med, 10.1111/jcmm.17912
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Whole-Genome Methylation Sequencing Reveals that COVID-19-induced Epigenetic Dysregulation Remains 1 Year after Hospital Discharge

  • Joseph Balnis, Andy Madrid, Kirk J Hogan, …, Harold A Singer, Reid S Alisch, Ariel Jaitovich
  • Am J Respir Cell Mol Biol, 10.1165/rcmb.2022-0433le
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Mammalian aging driven by transcription going awry

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DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation

  • Matyas Jokai, Ferenc Torma, Kristen M McGreevy, …, Kelvin J A Davies, Steve Horvath, Zsolt Radak
  • Geroscience, 10.1007/s11357-023-00826-1
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The Aging Biomarker Consortium represents a new era for aging research in China

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2022 Articles

4 046 articles

DNA methylation GrimAge version 2

  • Ake T Lu, Alexandra M Binder, Joshua Zhang, …, Luigi Ferrucci, Riccardo E Marioni, Steve Horvath
  • Aging (Albany NY), 10.18632/aging.204434
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Single short reprogramming early in life increases healthspan

  • Jean-Marc Lemaitre, Ollivier Milhavet, Ollivier Milhavet, …, Jean-Marc Lemaitre, Ollivier Milhavet, Jean-Marc Lemaitre
  • Aging (Albany NY), 10.18632/aging.204457
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The challenges and opportunities of scRNA-seq in COVID-19 research and clinical translation

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The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging

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Epigenetic age acceleration is associated with oligodendrocyte proportions in MSA and control brain tissue

  • Megha Murthy, Gemma Shireby, Yasuo Miki, …, Thomas T Warner, Jonathan Mill, Conceição Bettencourt
  • Neuropathol Appl Neurobiol, 10.1111/nan.12872
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A Targeted Epigenetic Clock for the Prediction of Biological Age

  • Noémie Gensous, Claudia Sala, Chiara Pirazzini, …, Claudio Franceschi, Maria Giulia Bacalini, Paolo Garagnani
  • Cells, 10.3390/cells11244044
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Epigenetic clocks, aging, and cancer

  • Sarah E Johnstone, Vadim N Gladyshev, Martin J Aryee, …, Vadim N Gladyshev, Martin J Aryee, Bradley E Bernstein
  • Science, 10.1126/science.abn4009
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Epigenetic clocks provide clues to the mystery of uterine ageing

  • Pavel I Deryabin, Aleksandra V Borodkina, Pavel I Deryabin, Aleksandra V Borodkina, Pavel I Deryabin, Aleksandra V Borodkina
  • Hum Reprod Update, 10.1093/humupd/dmac042
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A comparison of the genes and genesets identified by GWAS and EWAS of fifteen complex traits

  • Tom R Gaunt, Caroline L Relton, Nicholas J Timpson, …, Caroline L Relton, Nicholas J Timpson, Gibran Hemani
  • Nat Commun, 10.1038/s41467-022-35037-3
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Leukocyte DNA methylation in Alzheimer´s disease associated genes: replication of findings from neuronal cells

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